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Starting with diethyl malonate and using any other reagents of your choice, propose an efficient synthesis for the following compound: EtO OEt The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer.

Starting with diethyl malonate and using any other reagents of your choice, propose an efficient synthesis for the following compound: EtO OEt The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Starting with diethyl malonate and using any other reagents of your choice, propose an efficient synthesis for the following compound: [Image of chemical reaction transforming diethyl malonate to a new compound] The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. **Options:** - **A** - Image of a bromoethane structure. - **B** - Image of a bromopropane structure. - **C** - CH₃CH₂Br - **D** - NaOEt - **E** - Br₂, H₃O⁺ - **F** - EtOH, [H⁺] - **G** - H₃O⁺, heat - **H** - NaCN - **I** - 1) EtMgBr; 2) H₃O⁺ [Note: Users should select the appropriate reagents to describe the complete synthesis pathway for the compound.]
Transcribed Image Text:Starting with diethyl malonate and using any other reagents of your choice, propose an efficient synthesis for the following compound: [Image of chemical reaction transforming diethyl malonate to a new compound] The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. **Options:** - **A** - Image of a bromoethane structure. - **B** - Image of a bromopropane structure. - **C** - CH₃CH₂Br - **D** - NaOEt - **E** - Br₂, H₃O⁺ - **F** - EtOH, [H⁺] - **G** - H₃O⁺, heat - **H** - NaCN - **I** - 1) EtMgBr; 2) H₃O⁺ [Note: Users should select the appropriate reagents to describe the complete synthesis pathway for the compound.]
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This reaction is simple deprotonation of active methylene centre followed by alkylation and then ester hydrolysis followed by decarboxylation under heating condition.

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