Neutral Amino Acids
Amino acids which do not have any charge on them are neutral amino acids.
Globular Protein
The globular proteins refer to the shape of protein specifically spherical in nature apart from spherical form fibrous, disordered and membrane-bound proteins exist. These globular proteins are miscible in water and form a colloidal solution rather than other types which might not exhibit solubility. Many classes of the fold are found in globular proteins, which render them a sphere shape. Globular fold containing proteins usually are referred to by the term globin.
Dimer
Dimers are basic organic compounds, which are derivates of oligomers. It is formed by the combination of two monomers which could potentially be strong or weak and in most cases covalent or intermolecular in nature. Identical monomers are called homodimer, the non-identical dimers are called heterodimer. The method by which dimers are formed is known as “dimerization”.
Dipeptide
A dipeptide is considered a mixture of two distinct amino acids. Since the amino acids are distinct, based on their composition, two dipeptide's isomers can be produced. Various dipeptides are biologically essential and are therefore crucial to industry.
The protein ribonuclease A in its native, or most stable,
form is folded into a compact globular shape:
(a) Does the native form have a lower or higher free
energy than the denatured form, in which the protein is
an extended chain? (b) What is the sign of the system’s
entropy change in going from the denatured to the
folded form? (c) In the native form, the molecule has
four ¬S¬S¬ bonds that bridge parts of the chain.
What effect do you predict these four linkages to have on
the free energy and entropy of the native form relative
to the free energy and entropy of a hypothetical folded
structure that does not have any ¬S¬S¬ linkages?
Explain. (d) A gentle reducing agent converts the four
¬S¬S¬ linkages in ribonuclease A to eight ¬S¬H
bonds. What effect do you predict this conversion to have
on the tertiary structure and entropy of the protein? (e)
Which amino acid must be present for ¬SH bonds to
exist in ribonuclease A?
Step by step
Solved in 4 steps with 4 images
