small and weak incisor teeth and with 8 posterior molars. The men thus affected have very little hair on the body and become bald early in life...It is remarkable that no instance has occurred of a daughter being affected... Although the daughters are never affected, they transmit the tendency to their sons; and no case has occurred of a son transmitting it to his sons." In additional families with the disorder, some females are mildly affected with small or malformed teeth and abnormal sweat glands. The lack of hair and sweat glands were patchy, with only some areas of skin affected. A test to detect female carriers reveals patchy distribution of sweat glands on the back. A. Mode of Inheritance is because: B. Is the phenotype sex-limited? Why or why not? C. The probability that a son of a woman who has patchy symptoms inherits anhidrotic ectodermal dysplasia is: D. For a woman to have a case as severe as an affected male, possible genotypes of her parents would be?

Human Anatomy & Physiology (11th Edition)
11th Edition
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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1. In 1875, Charles Darwin described a family with anhidrotic ectodermal dysplasia.
“Ten men, in 4 generations, where furnished, in both jaws taken together, with only 4
small and weak incisor teeth and with 8 posterior molars. The men thus affected have
very little hair on the body and become bald early in life...It is remarkable that no
instance has occurred of a daughter being affected... Although the daughters are never
affected, they transmit the tendency to their sons; and no case has occurred of a son
transmitting it to his sons."
In additional families with the disorder, some females are mildly affected with small or
malformed teeth and abnormal sweat glands. The lack of hair and sweat glands were
patchy, with only some areas of skin affected. A test to detect female carriers reveals
patchy distribution of sweat glands on the back.
A. Mode of Inheritance is
because:
B. Is the phenotype sex-limited? Why or why not?
C. The probability that a son of a woman who has patchy symptoms inherits anhidrotic
ectodermal dysplasia is:
D. For a woman to have a case as severe as an affected male, possible genotypes of her
parents would be?
Transcribed Image Text:1. In 1875, Charles Darwin described a family with anhidrotic ectodermal dysplasia. “Ten men, in 4 generations, where furnished, in both jaws taken together, with only 4 small and weak incisor teeth and with 8 posterior molars. The men thus affected have very little hair on the body and become bald early in life...It is remarkable that no instance has occurred of a daughter being affected... Although the daughters are never affected, they transmit the tendency to their sons; and no case has occurred of a son transmitting it to his sons." In additional families with the disorder, some females are mildly affected with small or malformed teeth and abnormal sweat glands. The lack of hair and sweat glands were patchy, with only some areas of skin affected. A test to detect female carriers reveals patchy distribution of sweat glands on the back. A. Mode of Inheritance is because: B. Is the phenotype sex-limited? Why or why not? C. The probability that a son of a woman who has patchy symptoms inherits anhidrotic ectodermal dysplasia is: D. For a woman to have a case as severe as an affected male, possible genotypes of her parents would be?
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