a) explain why a diagnosis of ASD is not possible in young babies. b) Given the current understanding of the concordance of ASD, if one of the children detected in these data was an identical twin, how certain is that the other twin would also meet the diagnostic criteria for ASD?
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- E. D. A. B. 11. C. Huntington's disease is a degenerative disease of the nervous system that strikes in middle age. The allele that causes the disease (H) is dominant to the allele that results in the normal condition (h). Answer the following questions about the inheritance of this disease. What is the genotype of a man who is normal but whose father had Huntington's disease? What is the genotype of a woman who has Huntington's disease if both of her parents had Huntington's disease? If a man who is heterozygous for Huntington's disease marries a woman who is normal, what would you expect for the genotypes and phenotypes of their children? If a normal man marries a woman who is homozygous for Huntington's disease, what do you expect for the genotypes and phenotypes of their children? Since Huntington's disease is caused by a dominant allele, does this mean it's also the most common allele in the population? F. Since Huntington's disease is caused by a dominant allele, does this mean…Over a thousand different alleles at the CFTR locus have been discovered that can cause cystic fibrosis. What difficulties might the presence of so many different alleles at this locus create for the diagnosis and treatment of cystic fibrosis?A survey of Canadian adult males was performed during the 1980s. 52% of the respondents smoked. The lifetime probability of a smoker getting lung cancer was 17.2%, whereas a non-smoker had a cancer probability of 1.3%. a)What is the conditional probability of a male smoker getting lung cancer? b)Draw a probability tree showing the probability of getting lung cancer conditional on smoking or not smoking. c)Using the tree, calculate the probability of smoking and getting lung cancer d)Show the same calculation as c), but in the format of the general multiplication rule Pr[A and B] = Pr[A] Pr[B|A] e)What is the probability that a male did not smoke and did not get lung cancer? pls help with the following. explain and make sure its 100 % accurate, thanks
- Neural Tube Defects (NTDs) are one of the most severe congenital malformations. A study was conducted to determine whether supplementation with folic acid or a mixture of seven other vitamins (A, D, B1, B2, B6, C, and nicotinamide) around the time of conception could prevent neural tube defects. A total of 1817 women at high risk of having a pregnancy with a neural tube defect (because of a previous affected pregnancy) were allocated at random to one of four groups: 1) folic acid; 2) other vitamins; 3) both; 4) neither. 1195 had a completed pregnancy; 27 of these had a known neural tube defect, 6 in the folic acid groups and 21 in the two other groups. This resulted in a risk ratio= 0.28. Based on the results of the study, which of the following is an appropriate conclusion? a)There is no difference in the effect of folic acid on NTDs b) None of these c) Folic acid increases risk of NTDs d) Folic acid is protective against NTDsList the type of heredity (ie autosomal dominant and recessive, X-linked dominant and recessive, epistasis, polygenic, codominant) for color blindness, ABO Blood types, Rh factor, nail patella syndrome, Fragile X syndrome, Kleinfelter syndrome, Turner syndrome, Trisomy 21, CAIS, albinism, PKU.How is it possible Jonathan has the dominant disorder, Huntington’s Disease, if none of his family had it? a) The mutant allele remained ‘hidden’ in previous generations. b) He is homozygous for mutant huntingtin alleles unlike his grandparents, who are clearly heterozygous for the condition. c) The appearance of Huntington Disease in him might be the result of a new mutation appearing during his lifetime. d) His parents and grandparents were ashamed to admit they had it.
- Neural Tube Defects (NTDs) are one of the most severe congenital malformations. A study was conducted to determine whether supplementation with folic acid or a mixture of seven other vitamins (A, D, B1, B2, B6, C, and nicotinamide) around the time of conception could prevent neural tube defects. A total of 1817 women at high risk of having a pregnancy with a neural tube defect (because of a previous affected pregnancy) were allocated at random to one of four groups: 1) folic acid; 2) other vitamins; 3) both; 4) neither. 1195 had a completed pregnancy; 27 of these had a known neural tube defect, 6 in the folic acid groups and 21 in the two other groups. This resulted in a risk ratio= 0.28. What type of study design is this? a) Case-control b) Randomized controlled trial c) Prospective cohort d) Retrospective cohortQ15: A research team interested in mapping human genes discovered a new restriction length polymorphism (RFLP). The nature of the polymorphism is shown in the figure below: RESEARCH METHOD GAATTC CTTAAG GACTTC CTCAAG GAA CT TTC AAG GAGTTC CTCAAG Long fragments Short fragments Туре 1 homozygote Туре 2 homozygote Heterozygote S First, they test the RFLP in a family with the pedigree below. The individuals colored blue are affected by hemophelia, a blood clotting disease. а. Dad Mom daughter1 daughter2 son1 son1 b. Next, they genotyped (determined the RFLP polymorphism, type 1 or type 2) of daughter1's family with the results shown below: husband daughter1 ||Explain the term pleiotropy.