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Scenario A patlent arrives in emergency room after struggling to breathe and with astnma. In this disease state the patlents airways can signiicantly decrease in radius. They noted that they were exercising when the episode occurred. Question Stem: Considering the patient was exercising before the attack, their muscle tissue pH was lower than normal. Which of the attached hemoglobin dissociation curves would best represent the state of the hemoglobin in the individual at that point in time? Answers A - B A Curve 2 B Curve 1

Scenario A patlent arrives in emergency room after struggling to breathe and with astnma. In this disease state the patlents airways can signiicantly decrease in radius. They noted that they were exercising when the episode occurred. Question Stem: Considering the patient was exercising before the attack, their muscle tissue pH was lower than normal. Which of the attached hemoglobin dissociation curves would best represent the state of the hemoglobin in the individual at that point in time? Answers A - B A Curve 2 B Curve 1

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Scenario:** A patient arrives in the emergency room after struggling to breathe and is subsequently diagnosed with asthma. In this disease state, the patient’s airways can significantly decrease in radius. They noted that they were exercising when the episode occurred. **Question Stem:** Considering the patient was exercising before the attack, their muscle tissue pH was lower than normal. Which of the attached hemoglobin dissociation curves would best represent the state of the hemoglobin in the individual at that point in time? **Answers A - B** - **A** Curve 2 - **B** Curve 1 *Note: The image does not provide specific graphs or diagrams to describe.*
Transcribed Image Text:**Scenario:** A patient arrives in the emergency room after struggling to breathe and is subsequently diagnosed with asthma. In this disease state, the patient’s airways can significantly decrease in radius. They noted that they were exercising when the episode occurred. **Question Stem:** Considering the patient was exercising before the attack, their muscle tissue pH was lower than normal. Which of the attached hemoglobin dissociation curves would best represent the state of the hemoglobin in the individual at that point in time? **Answers A - B** - **A** Curve 2 - **B** Curve 1 *Note: The image does not provide specific graphs or diagrams to describe.*
### Oxygen-Hemoglobin Dissociation Curve The image presents a graph illustrating the relationship between the partial pressure of oxygen (P\(_{\text{O}_2}\)) and the percentage saturation of hemoglobin with oxygen. This graph is essential for understanding how oxygen binds to hemoglobin in the blood under different pressures. **Axes:** - The x-axis represents the partial pressure of oxygen (P\(_{\text{O}_2}\)) measured in millimeters of mercury (mm Hg), ranging from 0 to 110 mm Hg. - The y-axis represents the percentage of oxygen saturation of hemoglobin, ranging from 0% to 100%. **Curves:** 1. **Original Curve:** - The baseline or original curve sits in the middle of the three curves. It depicts the standard oxygen-hemoglobin dissociation curve. - Typically, this curve shows how hemoglobin saturation increases as P\(_{\text{O}_2}\) increases, following a sigmoidal shape. 2. **Curve 1:** - Positioned to the left of the original curve. - Suggests an increased affinity of hemoglobin for oxygen, indicating that hemoglobin holds onto oxygen more tightly. - This leftward shift could occur under conditions like decreased temperature or increased pH (alkalosis). 3. **Curve 2:** - Positioned to the right of the original curve. - Indicates a decreased affinity of hemoglobin for oxygen, meaning hemoglobin releases oxygen more readily. - This rightward shift might be observed in circumstances such as increased temperature, higher levels of CO2, or decreased pH (acidosis). ### Interpretation These curves demonstrate how various physiological and pathological states can affect hemoglobin's affinity for oxygen. Understanding these shifts is crucial in medical and biological contexts, such as adapting to high altitudes, managing respiratory diseases, and optimizing oxygen delivery in clinical settings.
Transcribed Image Text:### Oxygen-Hemoglobin Dissociation Curve The image presents a graph illustrating the relationship between the partial pressure of oxygen (P\(_{\text{O}_2}\)) and the percentage saturation of hemoglobin with oxygen. This graph is essential for understanding how oxygen binds to hemoglobin in the blood under different pressures. **Axes:** - The x-axis represents the partial pressure of oxygen (P\(_{\text{O}_2}\)) measured in millimeters of mercury (mm Hg), ranging from 0 to 110 mm Hg. - The y-axis represents the percentage of oxygen saturation of hemoglobin, ranging from 0% to 100%. **Curves:** 1. **Original Curve:** - The baseline or original curve sits in the middle of the three curves. It depicts the standard oxygen-hemoglobin dissociation curve. - Typically, this curve shows how hemoglobin saturation increases as P\(_{\text{O}_2}\) increases, following a sigmoidal shape. 2. **Curve 1:** - Positioned to the left of the original curve. - Suggests an increased affinity of hemoglobin for oxygen, indicating that hemoglobin holds onto oxygen more tightly. - This leftward shift could occur under conditions like decreased temperature or increased pH (alkalosis). 3. **Curve 2:** - Positioned to the right of the original curve. - Indicates a decreased affinity of hemoglobin for oxygen, meaning hemoglobin releases oxygen more readily. - This rightward shift might be observed in circumstances such as increased temperature, higher levels of CO2, or decreased pH (acidosis). ### Interpretation These curves demonstrate how various physiological and pathological states can affect hemoglobin's affinity for oxygen. Understanding these shifts is crucial in medical and biological contexts, such as adapting to high altitudes, managing respiratory diseases, and optimizing oxygen delivery in clinical settings.
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