Researchers use active-controlled trials to test new medications that are used to treat a particular illness against old medications used to treat the same illness. True False
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Researchers use active-controlled trials to test new medications that are used to treat a particular illness against old medications used to treat the same illness.
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- Identifying individuals with a high risk of Alzheimer’s disease usually involves a long series of cognitive tests. However, researchers have developed a 7-Minute Screen, which is a quick and easy way to accomplish the same goal. The question is whether the 7-Minute Screen is as effective as the complete series of tests. To address this question, Ijuin et al. (2008) administered both tests to a group of patients and compared the results. The following data represent results similar to those obtained in the study. Scores in 7minute-screen (Y) Scores in Cognitive series (X) 0 11 4 19 6 22 8 20 5 14 4 13 A) Calculate the Pearson correlation for these data. B) If the researchers centered the variable of 7-minute screen (i.e., every score in this variable minus its Mean), what would be the new value of correlation? C) Is the correlation statistically significant? Use a two-tailed test with α = .05.A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…Researchers investigate how the presence of cell phones influence the quality of human interaction. Subjects are randomly selected from a population and divided into an experimental group that is asked to leave their phones in the front of the room and a control group that are not asked to leave their cell phones at the front of the room. Subjects are left alone for 10 minutes and then asked to take a survey designed to measure quality of interactions they had with others in the experiment. What statistical test is appropriate?
- When neither the subject nor those having contact with the subject know the treatment assignment, the study is called unbiased. double-blind. blind. statistically significant. randomized.There is a current chemotherapy drug available that is extremely successful in treating an aggressive form of breast cancer. This drug has as a serious side effect in that 20% of the recipients will subsequently go on to develop ALL, an often untreatable and fatal form of leukemia. The pharmaceutical company is developing a modified version of this drug and long term clinical trials are being conducted on 214 women afflicted with this aggressive form of breast cancer. The trials have indicated 31 subsequent cases of ALL. State and test the hypothesis that there is no difference in the proportion of ALL cases between the two chemotherapy drugs against the alternative that there is a difference. Set alpha equal to 0.02A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…
- Teenagers who do not sleep well or long enough may have a higher risk of raised blood pressure, which could lead to cardiovascular disease later in life. The odds of raised blood pressure increase 3.5 times for those who have trouble falling asleep at night or who wake up too early and 2.5 times for those with sleeping periods of fewer than 6.5 hours. A health psychologist is interested in studying teenagers who have diastolic blood pressure scores in the top 20%. Diastolic blood pressure scores for teenagers follow a normal distribution with μ = 72 and σ = 10. Use the Distributions tool to help answer the questions that follow. The minimum z-score necessary to be in the top 20% of the diastolic blood pressure distribution is z =0.842 . Use this z-score to determine X, the corresponding diastolic blood pressure score. X = 80.42 This score, X, is the 80th percentile of diastolic blood pressure scores among teenagers. The percentile rank of this score is 80%…Identifying individuals with a high risk of Alzheimer's disease usually involves a long series of cognitive tests. However, researchers have developed a 7-Minute Screen, which is a quick and easy way to accomplish the same goal. The question is whether the 7-Minute Screen is as effective as the complete series of tests. To address this question, Ijuin et al. (2008) administered both tests to a group of patients and compared the results. The following data represent results similar to those obtained in the study. 7-Minute Screen Cognitive Series 3 11 8 19 10 22 8 20 4 14 7 13 4 9 5 20 14 25 Which statistical test would you select: Answer H0: Answer H1: Answer What is the coefficient that indicates the strength of the relationship? Answer =Answer What is the standard error? Answer What is the appropriate 95% CI? [ Answer , Answer ] What is the d-effect size? Answer What is the t-observed? Answer What is the actual p-value? Answer THREE decimal places…researcher suspects that the actual prevalence of generalized anxiety among children and adolescents is higher than the previously reported prevalence of generalized anxiety disorder among children and adolescents. The previously reported prevalence of generalized anxiety disorder among children and adolescents is 3.9%, and the researcher conducts a study to test the accuracy of the previously reported prevalence of generalized anxiety disorder by recruiting 98 children and adolescents from various pediatricians' offices and tests them for generalized anxiety disorder using the DSM-5. The researcher determines that the prevalence of generalized anxiety disorder among the participants of the study is 6.1%. What should the researcher's conclusion be for a 5% significance level? A. We reject H0 at the 5% level because -57.53 is less than -1.96. We do have statistically significant evidence to show the actual prevalence of generalized anxiety disorder among children and adolescents…
- A pharmaceutical company has developed a new drug called Antisubcillin to treat substance use disorder. They have just completed an experiment assessing the safety of the drug. To test safety, 100 rats were given 20 mg of Antisubcillin and 100 rats were given a placebo. The study was conducted as a double-blind controlled study and so the researchers did not know which rats were receiving the drug and which were receiving the placebo. The number of negative side effects displayed by each rat over the course of 8 weeks was recorded. Which statistical test should be used to analyze these data? z test one-sample t test independent samples t test dependent samples t testA clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…Identifying individuals with a high risk of Alzheimer’s disease usually involves a long series of cognitive tests. However, researchers have developed a 7-Minute Screen, which is a quick and easy way to accomplish the same goal. The question is whether the 7-Minute Screen is as effective as the complete series of tests. To address this question, Ijuin et al. (2008) administered both tests to a group of patients and compared the results. The following data represent results similar to those obtained in the study. Patient 7-Minute Screen Cognitive Series A 3 7 B 7 15 C 4 14 D 5 13 E 7 9 F 5 15 G 11 25 The alternative hypothesis in words and null hypothesis in symbols for a two-tailed test is