repressor unable to bind to the operator. How would this mutation affect the bacterium's ability to catabolize lactose? Would the mutant strain have an advantage over the wild-
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
Transformation Experiment in Bacteria
In the discovery of genetic material, the experiment conducted by Frederick Griffith on Streptococcus pneumonia proved to be a stepping stone.
Plasmids and Vectors
The DNA molecule that exists in a circular shape and is smaller in size which is capable of its replication is called Plasmids. In other words, it is called extra-chromosomal plasmid DNA. Vectors are the molecule which is capable of carrying genetic material which can be transferred into another cell and further carry out replication and expression. Plasmids can act as vectors.
Instructions: After reading the Khan academy article on the Lac operon, suppose that E. coli sustains a mutation in its gene for the lac operon repressor making the repressor unable to bind to the operator.
- How would this mutation affect the bacterium's ability to catabolize lactose?
- Would the mutant strain have an advantage over the wild-type strain?
Lac Operon is a small unit of gene control in E coli bacteria it contains operator region, promotor region and region for synthesis of structural enzyme.
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