Remembering that the wobble base of the tRNA is the5′ base of the anticodon:a. In human tRNAs, what are the sequences of allpossible anticodons that were originally transcribedwith A in the wobble position? (Assume this A isalways modified to I.)b. In human tRNAs, what are the sequences of allpossible anticodons that were originally transcribedwith U in the wobble position? (Note: Any singletype of tRNA with a U at the wobble position canbe modified only in a single way.)c. How might the wobble Us in each of the anticodonsin (b) be modified and still be consistent with thegenetic code?d. What is the theoretical minimal number ofdifferent tRNA genes that must exist in thehuman genome? (Assume that xo5U pairs with A,G, or U only.)
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Remembering that the wobble base of the tRNA is the
5′ base of the anticodon:
a. In human tRNAs, what are the sequences of all
possible anticodons that were originally transcribed
with A in the wobble position? (Assume this A is
always modified to I.)
b. In human tRNAs, what are the sequences of all
possible anticodons that were originally transcribed
with U in the wobble position? (Note: Any single
type of tRNA with a U at the wobble position can
be modified only in a single way.)
c. How might the wobble Us in each of the anticodons
in (b) be modified and still be consistent with the
genetic code?
d. What is the theoretical minimal number of
different tRNA genes that must exist in the
human genome? (Assume that xo5
U pairs with A,
G, or U only.)
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