Read the following study, construct the appropriate 2x2 table, calculate the measure of association, state the study design, and state the interpretation of the results. A statewide outbreak of E. coli O:157 is being investigated. Confirmed cases of are being reported from several counties in Michigan. The suspected source of the E. coli O:157 is beef from a particular distributor. Investigators decided to investigate the association between E. coli O:157 and the beef by randomly select 50 households with a case living in the household and 50 control households from southeast Michigan. The households were asked whether they had purchased beef from this particular distributor. Among the households with a case of E. coli O:157 infection, 41 reported a history of buying beef from the distributor. Among the healthy control households, 16 gave a history of recently buying beef from this distributor. 2x2 table   + -

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Read the following study, construct the appropriate 2x2 table, calculate the measure of association, state the study design, and state the interpretation of the results.

A statewide outbreak of E. coli O:157 is being investigated. Confirmed cases of are being reported from several counties in Michigan. The suspected source of the E. coli O:157 is beef from a particular distributor. Investigators decided to investigate the association between E. coli O:157 and the beef by randomly select 50 households with a case living in the household and 50 control households from southeast Michigan. The households were asked whether they had purchased beef from this particular distributor. Among the households with a case of E. coli O:157 infection, 41 reported a history of buying beef from the distributor. Among the healthy control households, 16 gave a history of recently buying beef from this distributor.

  • 2x2 table

 

+

-

Total

+

A

B

A+B

-

C

D

C+D

Total

A+C

B+D

A+B+C+D

 

  • List the values for each cell: A, B, C, D, A+B, C+D, A+C, B+D, A+B+C+D
  • What type of study design is this?
  • What measure of association should be used for this study?
  • Calculate the measure of association (show your work)
  • State your interpretation

 

 

 

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