Ranitidine sulfur-containing side chain has substituted guanidine with pka of 2.7 for the secondary amine. Thus, this side chain is thus at physiological pH? N-CH₂ H₂C Rantine Ch NO₂ Currently Selected: B A lonized, protonated B Unionized, Deprotonated Clonized, deprotonated D Unionized, profonated and

Organic Chemistry
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ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
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Chapter27: Amino Acids And Proteins
Section: Chapter Questions
Problem 27.39P: A chemically modified guanidino group is present in cimetidine (Tagamet), a widely prescribed drug...
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Ranitidine sulfur-containing side chain has substituted guanidine with pka of 2.7 for the secondary amine. Thus, this side chain is thus
at physiological pH?
N-CH₂
Rantine
CH₂
NO₂
Currently Selected: B
A lonized; protonated
B Unionized, Deprotonated
Clonized, deprotonated
D Unionized, profonated
and
Transcribed Image Text:Ranitidine sulfur-containing side chain has substituted guanidine with pka of 2.7 for the secondary amine. Thus, this side chain is thus at physiological pH? N-CH₂ Rantine CH₂ NO₂ Currently Selected: B A lonized; protonated B Unionized, Deprotonated Clonized, deprotonated D Unionized, profonated and
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