Quinolines, heterocyclic compounds that contain a pyridine ring fused to a benzene ring, are commonly synthesized by a method known as the Skraup Synthesis, in which aniline reacts with glycerol under acidic conditions. Nitrobenzene is added to the reaction mixture to serve as an oxidizing agent. The first step in the synthesis is the dehydration of glycerol to propenal. What starting materials are needed for the synthesis of 2,7- diethyl-3-methylquinoline? Hint: Figure out the mechanism of the synthesis. quinoline N

Quinolines, heterocyclic compounds that contain a pyridine ring fused to a benzene ring, are commonly synthesized by a method known as the Skraup Synthesis, in which aniline reacts with glycerol under acidic conditions. Nitrobenzene is added to the reaction mixture to serve as an oxidizing agent. The first step in the synthesis is the dehydration of glycerol to propenal. What starting materials are needed for the synthesis of 2,7- diethyl-3-methylquinoline? Hint: Figure out the mechanism of the synthesis. quinoline N

Chemistry

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ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

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Concept explainers

Diol

In chemistry there are so many chemical compounds that have a hydroxyl group but a chemical compound having two hydroxyl groups (-OH) is termed as a diol. It also implies the presence of two alcohols whereas polyols contain two or more than two hydroxyl groups (-OH). Glycol or 1,2-diol is an aliphatic diol that has two alcohol groups on adjacent carbon atoms. In industries, the most commonly used diol is ethylene glycol.

Question

7. Quinolines, heterocyclic compounds that contain a pyridine ring fused to a benzene ring,
are commonly synthesized by a method known as the Skraup Synthesis, in which aniline
reacts with glycerol under acidic conditions. Nitrobenzene is added to the reaction
mixture to serve as an oxidizing agent. The first step in the synthesis is the dehydration
of glycerol to propenal. What starting materials are needed for the synthesis of 2,7-
diethyl-3-methylquinoline? Hint: Figure out the mechanism of the synthesis.
quinoline

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