Suppose you're out of acetic acid (CH3COOH) and decide to use ethanol (CH3 CH;OH) as the solvent in the transformation of 3 into 4. Would this be a wise choice, and why? NH2 CH,COOH

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3. Suppose you're out of acetic acid (CH;COOH) and decide to use ethanol (CH3 CH2OH) as the
solvent in the transformation of 3 into 4. Would this be a wise choice, and why?
ZHN
CH;COOH
H
Transcribed Image Text:3. Suppose you're out of acetic acid (CH;COOH) and decide to use ethanol (CH3 CH2OH) as the solvent in the transformation of 3 into 4. Would this be a wise choice, and why? ZHN CH;COOH H
REFER TO THE SCHEME FOR THE SYNTHESIS OF LIDOCAINE SHOWN BELOW
NO2 SnCl,/ HCI
NH3 CI
NH2
Кон
CH,COOH
CH;COOH
1
2
3
2,6-Dimethy-
2,6-Dimethy-
nitrobenzene
aniline
H
toluene
5
a-Chloro-2,6-
Lidocaine
dimethylacetanilide
Transcribed Image Text:REFER TO THE SCHEME FOR THE SYNTHESIS OF LIDOCAINE SHOWN BELOW NO2 SnCl,/ HCI NH3 CI NH2 Кон CH,COOH CH;COOH 1 2 3 2,6-Dimethy- 2,6-Dimethy- nitrobenzene aniline H toluene 5 a-Chloro-2,6- Lidocaine dimethylacetanilide
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