Questions 12-14: Results of a randomized clinical trial of a new vaccine formulated to protect against SARS CoV-2 infection are shown in the following table. A total of 100,000 adults who were negative for infection at baseline enrolled in the study. Estimates shown in the following table are based on results after follow-up of six months. SARS COV-2 SARS COV-2 Status Total Subjects Positive Negative Received Vaccine 10 49,990 50,000 Did not receive vaccine 200 49,810 50,000 2. What is the main measure of interest in the study? 2 A. Relative Risk. OC. The fraction of disease attributable to SARS CoV-2 for exposed persons. OB. Odds Ratio. O D. The fraction of disease attributable to SAR CoV-2 for non-exposed persons.

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### Clinical Trial Results on the Efficacy of a New Vaccine Against SARS CoV-2

#### Study Overview

A randomized clinical trial was conducted to evaluate a new vaccine designed to protect against SARS CoV-2 infection. The study enrolled 100,000 adults who tested negative for the infection at baseline. The data presented below are based on the results after a follow-up period of six months.

#### Results Table

| Status                | SARS CoV-2 Positive | SARS CoV-2 Negative | Total Subjects |
|-----------------------|---------------------|---------------------|----------------|
| **Received Vaccine**  | 10                  | 49,990              | 50,000         |
| **Did not receive vaccine** | 200                | 49,810              | 50,000         |

- **Received Vaccine**: 
  - SARS CoV-2 Positive: 10 
  - SARS CoV-2 Negative: 49,990
  - Total Subjects: 50,000

- **Did Not Receive Vaccine**:
  - SARS CoV-2 Positive: 200
  - SARS CoV-2 Negative: 49,810
  - Total Subjects: 50,000

#### Question

12. What is the main measure of interest in the study?

- A. Relative Risk.
- B. Odds Ratio.
- C. The fraction of disease attributable to SARS CoV-2 for exposed persons.
- D. The fraction of disease attributable to SARS CoV-2 for non-exposed persons.

This table is crucial for understanding the comparative effectiveness of the vaccine in preventing SARS CoV-2 infection among the vaccinated versus the unvaccinated groups.
Transcribed Image Text:### Clinical Trial Results on the Efficacy of a New Vaccine Against SARS CoV-2 #### Study Overview A randomized clinical trial was conducted to evaluate a new vaccine designed to protect against SARS CoV-2 infection. The study enrolled 100,000 adults who tested negative for the infection at baseline. The data presented below are based on the results after a follow-up period of six months. #### Results Table | Status | SARS CoV-2 Positive | SARS CoV-2 Negative | Total Subjects | |-----------------------|---------------------|---------------------|----------------| | **Received Vaccine** | 10 | 49,990 | 50,000 | | **Did not receive vaccine** | 200 | 49,810 | 50,000 | - **Received Vaccine**: - SARS CoV-2 Positive: 10 - SARS CoV-2 Negative: 49,990 - Total Subjects: 50,000 - **Did Not Receive Vaccine**: - SARS CoV-2 Positive: 200 - SARS CoV-2 Negative: 49,810 - Total Subjects: 50,000 #### Question 12. What is the main measure of interest in the study? - A. Relative Risk. - B. Odds Ratio. - C. The fraction of disease attributable to SARS CoV-2 for exposed persons. - D. The fraction of disease attributable to SARS CoV-2 for non-exposed persons. This table is crucial for understanding the comparative effectiveness of the vaccine in preventing SARS CoV-2 infection among the vaccinated versus the unvaccinated groups.
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