Question -The FDA has authorized the use of direct-to-consumer testing for three mutations in BRCA genes that elevate cancer risk, but cautions that a negative result does not rule out increased cancer risk. How can this be true? A. It is impossible to trust companies that are selling genetic tests. B. They have a conflict of interest, and so the tests should be used for entertainment value only C. These tests are not highly accurate, and false negatives are possible. Individuals with a family history should have a negative result confirmed with a different test to be sure they are truly at low risk of developing cancer There are more ways to get cancer than a mutation in the BRCA gene. D. The test only detects three out of more than 1,000 known BRCA mutations. This means a negative result does not rule out the possibility that an individual carries other BRCA mutations that increase cancer risk.
Question -The FDA has authorized the use of direct-to-consumer testing for three mutations in BRCA genes that elevate cancer risk, but cautions that a negative result does not rule out increased cancer risk. How can this be true?
A. It is impossible to trust companies that are selling genetic tests.
B. They have a conflict of interest, and so the tests should be used for entertainment value only
C. These tests are not highly accurate, and false negatives are possible. Individuals with a family history should have a negative result confirmed with a different test to be sure they are truly at low risk of developing cancer There are more ways to get cancer than a mutation in the BRCA gene.
D. The test only detects three out of more than 1,000 known BRCA mutations. This means a negative result does not rule out the possibility that an individual carries other BRCA mutations that increase cancer risk..
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