Question 9: [30 pts] 0 Illustrated below is the mechanism of (A) base-catalyzed hydrolysis of a cyclic anhydride and (B) bromolactonization. Clearly describe each elementary step (-i) shown of the mechanism. In CHE 232 lecture, we are currently discussing carboxylic acid derivatives, so you should be able to thoroughly describe (in words!) the anhydride hydrolysis. SAc-Base Catalyzed H Anhydride Hydrolysis H H +[H₂O]/[HCO₂H] H Na / OH L Na Collapse of tetrahedral intermediate with Ring opening -[H] OH Na°/0° Br Br 11. Na/ AdE- Electrophilic Additon of Bromine +[Br III. H O/Na Br H Br Br H H Na H -0°/Na Lactonization —[NaBr] Na bridged bromonium ion

Question 9: [30 pts] 0 Illustrated below is the mechanism of (A) base-catalyzed hydrolysis of a cyclic anhydride and (B) bromolactonization. Clearly describe each elementary step (-i) shown of the mechanism. In CHE 232 lecture, we are currently discussing carboxylic acid derivatives, so you should be able to thoroughly describe (in words!) the anhydride hydrolysis. SAc-Base Catalyzed H Anhydride Hydrolysis H H +[H₂O]/[HCO₂H] H Na / OH L Na Collapse of tetrahedral intermediate with Ring opening -[H] OH Na°/0° Br Br 11. Na/ AdE- Electrophilic Additon of Bromine +[Br III. H O/Na Br H Br Br H H Na H -0°/Na Lactonization —[NaBr] Na bridged bromonium ion

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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