Question 6:   Determine the sequence of amino acids specified by the codons in the following information strand.   AGG TCT TCA GGG AAT GCC TGG CGA GAG GGG AGC AGC TGG TAT CGC TGG GCC CAA

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Question 6:

 

Determine the sequence of amino acids specified by the codons in the following information strand.

 

AGG

TCT

TCA

GGG

AAT

GCC

TGG

CGA

GAG

GGG

AGC

AGC

TGG

TAT

CGC

TGG

GCC

CAA

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Then determine the sequence of amino acids if an insertion occurred to the left of the first adenosine and changed the reading frame as shown below. Notice that (1) the insertion is shown on the left by the lower-case “i”, and (2) the bases are still in the same sequence; they are just shifted so that they are read differently.

 

 

iAG

GTC

TTC

AGG

GAA

TGC

CTG

GCG

AGA

GGG

GAG

CAG

CTG

GTA

TCG

CTG

GGC

CCA

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Suppose a single-nucleotide polymorphism occurred in the original strand to make the change shown below. Would this affect the resulting protein? Explain.

 

 

AGG

TCT

TCA

GGG

AAT

GCC

TGG

CGA

GAG

GGG

AGC

AGC

TGG

TAT

CGC

TGG

GCC

CAA

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

This is the original strand

 

 

AGG

TCT

TCA

GGG

AAT

GCC

TGG

CGA

GAG

GGG

AGC

AGC

TAG

TAT

CGC

TGG

GCC

CAA

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

This is the strand with the SNP. (The change is shown in red.)

 

Suppose a different single-nucleotide polymorphism occurred in the original strand to make the change shown below. Would this affect the resulting protein? Explain.

 

 

AGG

TCT

TCA

GGG

AAT

GCC

TGG

CGA

GAG

GGG

AGC

AGC

TGG

TAT

CGC

TGG

GCC

CAA

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

This is the original strand

 

 

AGG

TCT

TCA

GGG

AAT

GCC

TGG

CGA

GAG

GGA

AGC

AGC

TGG

TAT

CGC

TGG

GCC

CAA

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

This is the mutated strand. (The change is shown in red).

 

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