Question 6: Determine the sequence of amino acids specified by the codons in the following information strand. AGG TCT TCA GGG AAT GCC TGG CGA GAG GGG AGC AGC TGG TAT CGC TGG GCC CAA
Coding Strand of DNA
When pointing to DNA transcription, the coding strand is found to be the DNA strand whose base sequence is indistinguishable from the base sequence of the RNA transcript developed. It is this strand that comprises the codons, while the non-coding strand comprises the anti-codons.
Nucleotide
Both DNA and RNA are composed of organic molecules known as nucleotides. Hence, nucleotides are known as the basic building blocks of nucleic acids. These substances play a role in various processes such as cell signalling, enzyme reactions, metabolism, and so on.
Structure of Cytosine
Cytosine is among the five primary nitrogenous bases of which DNA and RNA and are being used in storage and transportation of genetic makeup within a cell. Adenine, guanine, thymine as well as uracil are the remaining four nucleobases.
Question 6:
Determine the sequence of amino acids specified by the codons in the following information strand.
AGG |
TCT |
TCA |
GGG |
AAT |
GCC |
TGG |
CGA |
GAG |
GGG |
AGC |
AGC |
TGG |
TAT |
CGC |
TGG |
GCC |
CAA |
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Then determine the sequence of amino acids if an insertion occurred to the left of the first adenosine and changed the reading frame as shown below. Notice that (1) the insertion is shown on the left by the lower-case “i”, and (2) the bases are still in the same sequence; they are just shifted so that they are read differently.
iAG |
GTC |
TTC |
AGG |
GAA |
TGC |
CTG |
GCG |
AGA |
GGG |
GAG |
CAG |
CTG |
GTA |
TCG |
CTG |
GGC |
CCA |
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Suppose a single-
AGG |
TCT |
TCA |
GGG |
AAT |
GCC |
TGG |
CGA |
GAG |
GGG |
AGC |
AGC |
TGG |
TAT |
CGC |
TGG |
GCC |
CAA |
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This is the original strand
AGG |
TCT |
TCA |
GGG |
AAT |
GCC |
TGG |
CGA |
GAG |
GGG |
AGC |
AGC |
TAG |
TAT |
CGC |
TGG |
GCC |
CAA |
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This is the strand with the SNP. (The change is shown in red.)
Suppose a different single-nucleotide polymorphism occurred in the original strand to make the change shown below. Would this affect the resulting protein? Explain.
AGG |
TCT |
TCA |
GGG |
AAT |
GCC |
TGG |
CGA |
GAG |
GGG |
AGC |
AGC |
TGG |
TAT |
CGC |
TGG |
GCC |
CAA |
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This is the original strand
AGG |
TCT |
TCA |
GGG |
AAT |
GCC |
TGG |
CGA |
GAG |
GGA |
AGC |
AGC |
TGG |
TAT |
CGC |
TGG |
GCC |
CAA |
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This is the mutated strand. (The change is shown in red).
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