Provide an example of covalent catalysis in the mechanism of chymotrypsin.What is the nucleophile involved in the formation of this covalent bond? Whatenabled this group to become a good nucleophile?

Chymotrypsin is a digestive enzyme that hydrolyzes peptide bonds, specifically at the carboxyl side…

Answered: Provide an example of covalent…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Provide an example of covalent catalysis in the mechanism of chymotrypsin. What is the nucleophile involved in the formation of this covalent bond? What enabled this group to become a good nucleophile?