Propose an efficient synthesis for the following transformation: ※ース Br, Br The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one corre solution, provide just one answer. A C H20, H2SO4, HBSO4 Br2 HC=CNa E 1) O3 2) DMS H2, Lindlar's catalyst 1) R2BH 2) H2O2, NaOH H. 1) xs NaNH2 2) H20 t-BUOK H2, Pd
Reactive Intermediates
In chemistry, reactive intermediates are termed as short-lived, highly reactive atoms with high energy. They rapidly transform into stable particles during a chemical reaction. In specific cases, by means of matrix isolation and at low-temperature reactive intermediates can be isolated.
Hydride Shift
A hydride shift is a rearrangement of a hydrogen atom in a carbocation that occurs to make the molecule more stable. In organic chemistry, rearrangement of the carbocation is very easily seen. This rearrangement can be because of the movement of a carbocation to attain stability in the compound. Such structural reorganization movement is called a shift within molecules. After the shifting of carbocation over the different carbon then they form structural isomers of the previous existing molecule.
Vinylic Carbocation
A carbocation where the positive charge is on the alkene carbon is known as the vinyl carbocation or vinyl cation. The empirical formula for vinyl cation is C2H3+. In the vinyl carbocation, the positive charge is on the carbon atom with the double bond therefore it is sp hybridized. It is known to be a part of various reactions, for example, electrophilic addition of alkynes and solvolysis as well. It plays the role of a reactive intermediate in these reactions.
Cycloheptatrienyl Cation
It is an aromatic carbocation having a general formula, [C7 H7]+. It is also known as the aromatic tropylium ion. Its name is derived from the molecule tropine, which is a seven membered carbon atom ring. Cycloheptatriene or tropylidene was first synthesized from tropine.
Stability of Vinyl Carbocation
Carbocations are positively charged carbon atoms. It is also known as a carbonium ion.
![**Problem Statement:**
Propose an efficient synthesis for the following transformation:
**[Image Description:**
The image displays a chemical reaction where a molecule with two bromine atoms (Br) attached to a carbon skeleton is transformed into a carbonyl compound (a ketone).]
**Question:**
The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer.
**Reagents:**
**A:** H₂O, H₂SO₄, HgSO₄
**B:** Br₂
**C:** HC≡CNa
**D:**
1) O₃
2) DMS
**E:** H₂, Lindlar's catalyst
**F:**
1) R₂BH
2) H₂O₂, NaOH
**G:**
1) xs NaNH₂
2) H₂O
**H:** t-BuOK
**I:** H₂, Pd
Please enter the string of letters representing your answer.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F1131871b-8c87-406d-9807-6125c8d6ca38%2Fc1406cc6-61f5-4ba7-b8c8-a0fa535e3d0a%2Frfu1uwc_processed.jpeg&w=3840&q=75)
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