Predict the FINAL (?) product (or a mixture of products) for the following synthetic trans two diastereomers Br + Br A Br NaSH DMSO SN2 1. Os04 2. H₂O2 B Br Br 80 Br t-BuOK Hofmann product H₂ Pd catalyst Br C Br Br₂ Br ? ? two diastereomers Br 00.00.00 go Br D
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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![Predict the FINAL (?) product (or a mixture of products) for the following synthetic transformation:
two diastereomers
Br
O O
Br
O A
ОВ
A
Br
NaSH
DMSO
SN2
1. Os04
2. H₂O2
B
Br
80
Br
g
Br
t-BuOK
Hofmann product
H₂
Pd catalyst
Br
C
Br
Br₂
?
?
two diastereomers
00 00 00 00
Br
Br
Br
D](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F712b00ab-760d-436d-a850-418dcf285219%2Fa80b81f2-c04c-41d7-a5cf-ee70cd65b021%2Ftxm389_processed.png&w=3840&q=75)
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