Aspartic acid is a polyprotic system whose forms can be written as H3A+, H2A, HA-, and A2-. Its Ka values are: Ka1 = 1.02 x 10-2 Ka2 = 1.26 x 10-4 Ka3 = 9.95 x 10-11 How many milliliters of 0.30 M NaOH should be added to 100 mL of a solution containing 8.0 g of the neutral, zwitterionic form of aspartic acid (M.W. = 133.10 g/mol) to bring the pH to 10.3? Find the  answer to the nearest mL. The answer is between 300 and 400. Retain 4 d.p. in your calculations and don't round until you calculate the volume of NaOH required at the very end.

Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter14: Acids And Bases
Section14.8: Acid-base Reactions Of Salts
Problem 14.21CE
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Aspartic acid is a polyprotic system whose forms can be written as H3A+, H2A, HA-, and A2-. Its Ka values are:

Ka1 = 1.02 x 10-2

Ka2 = 1.26 x 10-4

Ka3 = 9.95 x 10-11

How many milliliters of 0.30 M NaOH should be added to 100 mL of a solution containing 8.0 g of the neutral, zwitterionic form of aspartic acid (M.W. = 133.10 g/mol) to bring the pH to 10.3?

Find the  answer to the nearest mL. The answer is between 300 and 400. Retain 4 d.p. in your calculations and don't round until you calculate the volume of NaOH required at the very end.

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