po. One endpoint reported was the occurrence of any skeletal events after 9 cycles of treat rence. ment 5 Pamidronate Placebo Occurrence of Skeletal Event Yes 47 74 121 No 149 107 256 196 181 377 percent of patients received pamidronate? What percent of patients experienced the occu al events?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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An efficacy study was conducted for the drug pamidronate in patients with stage III multiple myeloma and at least
one lytic lesion. In this randomized clinical trial, patients were assigned at random to receive either pamidronate or
placebo. One endpoint reported was the occurrence of any skeletal events after 9 cycles of treatment or non-
occurrence.
Treatment
Group
Pamidronate
Placebo
Occurrence of Skeletal Event
Yes
47
74
121
No
149
107
256
196
181
377
What percent of patients received pamidronate? What percent of patients experienced the occurrence of any
skeletal events?
Transcribed Image Text:An efficacy study was conducted for the drug pamidronate in patients with stage III multiple myeloma and at least one lytic lesion. In this randomized clinical trial, patients were assigned at random to receive either pamidronate or placebo. One endpoint reported was the occurrence of any skeletal events after 9 cycles of treatment or non- occurrence. Treatment Group Pamidronate Placebo Occurrence of Skeletal Event Yes 47 74 121 No 149 107 256 196 181 377 What percent of patients received pamidronate? What percent of patients experienced the occurrence of any skeletal events?
What do you learn from (a) - (c)? Is the drug pamidronate effective?
Transcribed Image Text:What do you learn from (a) - (c)? Is the drug pamidronate effective?
Expert Solution
Step 1

Drug efficacy study is intended to test the ability of an intervention for example, a drug  to produce the desired beneficial effect. Hear this desired beneficial effect is shown in the form of occurrence of skeletal events. 

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