Please help me with these questions based on the graph attached. More than one answer may be correct for each one: In patients with diabetes mellitus, a condition known as diabetic nephropathy can occur in which the kidneys are damaged.  The above figures show changes to GFR and glomerulus capillary fenestrations. 1) From the above figure, what is likely causing the decrease in GFR during diabetic nephropathy?      decreased fenestration width decreased mean arterial pressure increased fenestration width increase in fenestration density decrease in fenestration density 2) From the above figure, what could also occur as a result of diabetic nephropathy?      decreased vasopressin production decreased urine formation increased vasopressin production slower drug clearance from blood increase protein in urine

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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Please help me with these questions based on the graph attached. More than one answer may be correct for each one:

In patients with diabetes mellitus, a condition known as diabetic nephropathy can occur in which the kidneys are damaged.  The above figures show changes to GFR and glomerulus capillary fenestrations.

1) From the above figure, what is likely causing the decrease in GFR during diabetic nephropathy?

    
decreased fenestration width


decreased mean arterial pressure


increased fenestration width


increase in fenestration density


decrease in fenestration density

2) From the above figure, what could also occur as a result of diabetic nephropathy?
    
decreased vasopressin production


decreased urine formation


increased vasopressin production


slower drug clearance from blood


increase protein in urine

Control
Diabetes
Diabetes
Fenestration width (nm)
Control
Diabetes
Fenestration density (/pm)
0.0-
Control
-08
21.
HH
…….
▶
GFR (ml/min)
|
|-
****
Transcribed Image Text:Control Diabetes Diabetes Fenestration width (nm) Control Diabetes Fenestration density (/pm) 0.0- Control -08 21. HH ……. ▶ GFR (ml/min) | |- ****
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