Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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please draw the molecule and label it based on the data in the sheet and use the label in the data table.

Transcribed Image Text:Experiment 3: Williamson Ether Synthesis (Data sheet)
Setup:
4.5 g of potassium hydroxide were dissolved in 8 mL of water in a 250 mL round-bottomed
flask
2.55 g of p-cresol were added, and the mixture is swirled
The pale-yellow mixture was brought to gentle reflux and a 6.70 mL of a 50 % aqueous
solution (g/mL) of a-chloroacetic acid drop-wise using a separatory funnel
Running the reaction:
The mixture was refluxed for 10 minutes
Product isolation:
The hot mixture was transferred to a 100 mL beaker and 10 mL cold water was added
Concentrated hydrochloric acid was added dropwise until pH<2.
The yellowish mixture was placed in an ice bath for 20 minutes
The mixture was filtered using a 5 cm a Büchner funnel using a vacuum filtration setup
The crude product was recrystallized from 30 mL hot water
After filtration, the solids were placed in a drying oven at 100 °C
Product characterization:
2.30 g of a pale white solid
М.p.: 137-140 °C

Transcribed Image Text:NMR spectra (300 MHz, DMSO-d6) ('H-NMR lower spectrum, BC-NMR upper spectrum)
DMSO-d6
220
QE-300
240
200
180
160
140
120
100
80
60
40
20
Offset: 1.2 ppm
12
11
10
6.
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