Pilocarpine is a medication used in eye drop to manage angle closure glaucoma. It works by activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to open and the aqueous humor to drain from the eye. The diester compound in the left can serve as a prodrug for pilocarpine. Please provide a mechanism for this conversion using esterase.
Pilocarpine is a medication used in eye drop to manage angle closure glaucoma. It works by activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to open and the aqueous humor to drain from the eye. The diester compound in the left can serve as a prodrug for pilocarpine. Please provide a mechanism for this conversion using esterase.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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![Pilocarpine is a medication used in eye drop to manage angle closure glaucoma. It works by
activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to
open and the aqueous humor to drain from the eye. The diester compound in the left can serve as a
prodrug for pilocarpine. Please provide a mechanism for this conversion using esterase.
R2
pilocarpine
Diester prodrug for pilocarpine](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fcc176911-96ff-43fd-a747-a205e460a9ee%2F37a56e65-4d67-49e6-984c-efe9cb3562da%2Fxs2ckm_processed.png&w=3840&q=75)
Transcribed Image Text:Pilocarpine is a medication used in eye drop to manage angle closure glaucoma. It works by
activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to
open and the aqueous humor to drain from the eye. The diester compound in the left can serve as a
prodrug for pilocarpine. Please provide a mechanism for this conversion using esterase.
R2
pilocarpine
Diester prodrug for pilocarpine
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