Person witha normal phenotype who cartesa trunsiscted chremiome Tranalooted chromaaome cortaining long arma of chromame and 21 46 ,x*,14,१(14421) -21 14 -14 Gamete formation Pobie gamet 11 Fanketion uth anomal gamete Piblie rng 22 (b) Karyotypo of a malo with familial Down syndrome Famll Down yndrone Normal Eelanced cater Kinbelanced) Untanienced, kethal (m Poble tranamtaalom petem Transmission of familial Down syndrome. (a) Potential transmission of familial Down syndrome. The individual with the chromosome composition shown at the top of this figure may produce a gamete carrying chromosome 21 and a fused chromosome containing the long arms of chromosomes 14 and 21. Such a gamete can give rise to an offspring with familial Down syndrome. (b) The karyotype of an individual with familial Down syndrome. This karyotype shows that the long arm of chromosome 21 has been translocated to chromosome 14 (see red arrow). In addition, the individual also carries two normal copies of chromosome 21. (c) An individual (in the center) with this disorder.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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If these segregation patterns are equally likely, what is the probability that a gamete produced by the individual who carries the translocated
chromosome will result in a viable offspring with a normal phenotype?

Person witha normal phenotype who
cartesa trunsiscted chremiome
Tranalooted chromaaome
cortaining long arma of
chromame and 21
46 ,x*,14,१(14421)
-21
14
-14
Gamete formation
Pobie gamet
11
Fanketion
uth anomal
gamete
Piblie rng
22
(b) Karyotypo of a malo with familial Down syndrome
Famll Down
yndrone
Normal
Eelanced
cater
Kinbelanced)
Untanienced, kethal
(m Poble tranamtaalom petem
Transmission of familial Down syndrome. (a) Potential transmission of familial Down syndrome.
The individual with the chromosome composition shown at the top of this figure may produce a gamete
carrying chromosome 21 and a fused chromosome containing the long arms of chromosomes 14 and 21.
Such a gamete can give rise to an offspring with familial Down syndrome. (b) The karyotype of an individual
with familial Down syndrome. This karyotype shows that the long arm of chromosome 21 has been translocated
to chromosome 14 (see red arrow). In addition, the individual also carries two normal copies of chromosome 21.
(c) An individual (in the center) with this disorder.
Transcribed Image Text:Person witha normal phenotype who cartesa trunsiscted chremiome Tranalooted chromaaome cortaining long arma of chromame and 21 46 ,x*,14,१(14421) -21 14 -14 Gamete formation Pobie gamet 11 Fanketion uth anomal gamete Piblie rng 22 (b) Karyotypo of a malo with familial Down syndrome Famll Down yndrone Normal Eelanced cater Kinbelanced) Untanienced, kethal (m Poble tranamtaalom petem Transmission of familial Down syndrome. (a) Potential transmission of familial Down syndrome. The individual with the chromosome composition shown at the top of this figure may produce a gamete carrying chromosome 21 and a fused chromosome containing the long arms of chromosomes 14 and 21. Such a gamete can give rise to an offspring with familial Down syndrome. (b) The karyotype of an individual with familial Down syndrome. This karyotype shows that the long arm of chromosome 21 has been translocated to chromosome 14 (see red arrow). In addition, the individual also carries two normal copies of chromosome 21. (c) An individual (in the center) with this disorder.
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