Patient AE, weighing 9kg, is to be started on Co-Amoxiclav 50mg/kg/dose (Amoxicillin-based) every 8 hours for Pediatric Pneumonia via an intravenous drip. Reconstituted Co-Amoxiclav intravenous vials are only stable up to 4 hours upon preparation. Which commercially available variant is more suitable to be prescribed and dispensed for this patient, and what is the equivalent volume to be infused (in mL) per dose prescribed? Dilution: Co-Amoxiclav 600mg vial: dissolve contents in 10mL SWFI then further dilute in 50mL NSS; Co-Amoxiclav 1.2gm vial: dissolve contents in 20mL SWFI then further dilute in 100mL NSS. Note that further dilution volume is also related to the amount of drug.

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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  1. Patient AE, weighing 9kg, is to be started on Co-Amoxiclav 50mg/kg/dose (Amoxicillin-based) every 8 hours for Pediatric Pneumonia via an intravenous drip. Reconstituted Co-Amoxiclav intravenous vials are only stable up to 4 hours upon preparation. Which commercially available variant is more suitable to be prescribed and dispensed for this patient, and what is the equivalent volume to be infused (in mL) per dose prescribed?

    Dilution
    : Co-Amoxiclav 600mg vial: dissolve contents in 10mL SWFI then further dilute in 50mL NSS; Co-Amoxiclav 1.2gm vial: dissolve contents in 20mL SWFI then further dilute in 100mL NSS. Note that further dilution volume is also related to the amount of drug.
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