Part III: 1. For each metabolite listed in the table, describe its role in cellular respiration? a. Are they substrates or products? b. What is their main function?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Part III - Subcellular Metabolite Analysis
Detailed analysis of the damaged cells showed that ATP levels in the mitochondria were very low. Levels of pyruvate
and acetyl coenzyme A (CoA) were normal. You begin to suspect a malfunction of a specific cellular metabolic
pathway and so you request a more detailed analysis of the sub-cellular components of the affected cells from the
autopsy. The levels of key metabolites are reported below:
Average Metabolite Levels
Metabolite
Glucose
Pyruvate
NAD+
NADH
Average Patient Levels
99 μM
27 μM
το μΜ
400 μ.
Normal Levels
100 μ.
25 μM
75 µM
50 μΜ
Transcribed Image Text:Part III - Subcellular Metabolite Analysis Detailed analysis of the damaged cells showed that ATP levels in the mitochondria were very low. Levels of pyruvate and acetyl coenzyme A (CoA) were normal. You begin to suspect a malfunction of a specific cellular metabolic pathway and so you request a more detailed analysis of the sub-cellular components of the affected cells from the autopsy. The levels of key metabolites are reported below: Average Metabolite Levels Metabolite Glucose Pyruvate NAD+ NADH Average Patient Levels 99 μM 27 μM το μΜ 400 μ. Normal Levels 100 μ. 25 μM 75 µM 50 μΜ
Part III:
1. For each metabolite listed in the table, describe its role in cellular respiration?
a. Are they substrates or products?
b. What is their main function?
Transcribed Image Text:Part III: 1. For each metabolite listed in the table, describe its role in cellular respiration? a. Are they substrates or products? b. What is their main function?
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