Homework Help is Here – Start Your Trial Now!
Science
Biology
Part II-Autosomal Dominant Traits "Great, so this looks like an accurate representation of your family, right?" Dr. Ciletti asked. "Looks good to me," replied Greg. "My family is so small, there's not much to miss until you get to my grandparents," said Olga. "Well, factor VIII deficiency and myotonic dystrophy are inherited in completely different ways. Come to think of it, you asked about CF as well and ..." "CF" asked Greg. "Cystic fibrosis," Dr. Ciletti continued. "I was about to say that cystic fibrosis is inherited in a manner different than both of the other diseases you are concerned about, but let's tackle them one at a time." "Myotonic dystrophy is an autosomal dominant disease and it is the easiest to pick out of a pedigree. Now Greg, even though you have an uncle and aunt as well as a grandmother who all have the disease, you don't and there is no way that you will pass this disease on to your children. So that is the first piece of good news." "But don't a lot of genetic diseases skip a generation?" Greg asked. "And even if it doesn't, my mom has two siblings with the disease. Could she be a carrier and just pass the disease on to me? For that matter, could I be a carrier?" "Yes, could he be a carrier?" Olga added. "Absolutely not," Dr. Ciletti said. "Let me show you why." Questions 1. Do autosomal dominant disorders skip generations? 2. Could Greg or his mother be carriers of the gene that causes myotonic dystrophy? 3. Is there a possibility that Greg's aunt or uncle is homozygous for the myotonic dystrophy (MD) gene?

Part II-Autosomal Dominant Traits "Great, so this looks like an accurate representation of your family, right?" Dr. Ciletti asked. "Looks good to me," replied Greg. "My family is so small, there's not much to miss until you get to my grandparents," said Olga. "Well, factor VIII deficiency and myotonic dystrophy are inherited in completely different ways. Come to think of it, you asked about CF as well and ..." "CF" asked Greg. "Cystic fibrosis," Dr. Ciletti continued. "I was about to say that cystic fibrosis is inherited in a manner different than both of the other diseases you are concerned about, but let's tackle them one at a time." "Myotonic dystrophy is an autosomal dominant disease and it is the easiest to pick out of a pedigree. Now Greg, even though you have an uncle and aunt as well as a grandmother who all have the disease, you don't and there is no way that you will pass this disease on to your children. So that is the first piece of good news." "But don't a lot of genetic diseases skip a generation?" Greg asked. "And even if it doesn't, my mom has two siblings with the disease. Could she be a carrier and just pass the disease on to me? For that matter, could I be a carrier?" "Yes, could he be a carrier?" Olga added. "Absolutely not," Dr. Ciletti said. "Let me show you why." Questions 1. Do autosomal dominant disorders skip generations? 2. Could Greg or his mother be carriers of the gene that causes myotonic dystrophy? 3. Is there a possibility that Greg's aunt or uncle is homozygous for the myotonic dystrophy (MD) gene?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Topic Video
Question

Please help with part II of this case study (this is not a test but a homework assignment) 

Please answer questions 1-3

See PDF here https://docplayer.net/38967044-In-sickness-and-in-health-a-trip-to-the-genetic-counselor.html

Thank you!

NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE Part II-Autosomal Dominant Traits "Great, so this looks like an accurate representation of your family, right?" Dr. Ciletti asked. "Looks good to me," replied Greg. "My family is so small, there's not much to miss until you get to my grandparents," said Olga. "Well, factor VIII deficiency and myotonic dystrophy are inherited in completely different ways. Come to think of it, you asked about CF as well and ..." "CF" asked Greg. "Cystic fibrosis," Dr. Ciletti continued. "I was about to say that cystic fibrosis is inherited in a manner different than both of the other diseases you are concerned about, but let's tackle them one at a time." "Myotonic dystrophy is an autosomal dominant disease and it is the easiest to pick out of a pedigree. Now Greg, even though you have an uncle and aunt as well as a grandmother who all have the disease, you don't and there is no way that you will pass this disease on to your children. So that is the first piece of good news." "But don't a lot of genetic diseases skip a generation?" Greg asked. "And even if it doesn't, my mom has two siblings with the disease. Could she be a carrier and just pass the disease on to me? For that matter, could I be a carrier?" "Yes, could he be a carrier?" Olga added. "Absolutely not," Dr. Ciletti said. "Let me show you why." Questions I. Do autosomal dominant disorders skip generations? 2. Could Greg or his mother be carriers of the gene that causes myotonic dystrophy? 3. Is there a possibility that Greg's aunt or uncle is homozygous for the myotonic dystrophy (MD) gene? 4. Symptoms of myotonic dystrophy sometimes don't show up until after age fifty. What is the possibility that Greg's cousin has inherited the MD gene? 5. What is the possibility that Greg and Olga's children could inherit the MD gene? References Myotonic Dystrophy Fact Sheet http://www.mda.org.au/specific/mdamyt.html Human Genetics for First Year Students: Pedigree Construction http://www.uic.edu/classes/bms/bms655/lesson3.html "In Sickness and in Health" by Barry Chess Page 3
Transcribed Image Text:NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE Part II-Autosomal Dominant Traits "Great, so this looks like an accurate representation of your family, right?" Dr. Ciletti asked. "Looks good to me," replied Greg. "My family is so small, there's not much to miss until you get to my grandparents," said Olga. "Well, factor VIII deficiency and myotonic dystrophy are inherited in completely different ways. Come to think of it, you asked about CF as well and ..." "CF" asked Greg. "Cystic fibrosis," Dr. Ciletti continued. "I was about to say that cystic fibrosis is inherited in a manner different than both of the other diseases you are concerned about, but let's tackle them one at a time." "Myotonic dystrophy is an autosomal dominant disease and it is the easiest to pick out of a pedigree. Now Greg, even though you have an uncle and aunt as well as a grandmother who all have the disease, you don't and there is no way that you will pass this disease on to your children. So that is the first piece of good news." "But don't a lot of genetic diseases skip a generation?" Greg asked. "And even if it doesn't, my mom has two siblings with the disease. Could she be a carrier and just pass the disease on to me? For that matter, could I be a carrier?" "Yes, could he be a carrier?" Olga added. "Absolutely not," Dr. Ciletti said. "Let me show you why." Questions I. Do autosomal dominant disorders skip generations? 2. Could Greg or his mother be carriers of the gene that causes myotonic dystrophy? 3. Is there a possibility that Greg's aunt or uncle is homozygous for the myotonic dystrophy (MD) gene? 4. Symptoms of myotonic dystrophy sometimes don't show up until after age fifty. What is the possibility that Greg's cousin has inherited the MD gene? 5. What is the possibility that Greg and Olga's children could inherit the MD gene? References Myotonic Dystrophy Fact Sheet http://www.mda.org.au/specific/mdamyt.html Human Genetics for First Year Students: Pedigree Construction http://www.uic.edu/classes/bms/bms655/lesson3.html "In Sickness and in Health" by Barry Chess Page 3
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Mitochondrial mutations
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS