P18C.7 The study of conditions that optimize the association of proteins in solution guides the design of protocols for formation of large crystals that are amenable to analysis by X-ray diffraction techniques. It is important to characterize protein dimerization because the process is considered to be the rate-determining step in the growth of crystals of many proteins. Consider the variation with ionic strength of the rate constant at 298 K of dimerization in aqueous solution of a cationic protein P: I 0.0100 0.0150 0.0200 0.0250 0.0300 0.0350 8.10 13.30 20.50 27.80 38.10 52.00 What can be deduced about the charge of P?

P18C.7 The study of conditions that optimize the association of proteins in solution guides the design of protocols for formation of large crystals that are amenable to analysis by X-ray diffraction techniques. It is important to characterize protein dimerization because the process is considered to be the rate-determining step in the growth of crystals of many proteins. Consider the variation with ionic strength of the rate constant at 298 K of dimerization in aqueous solution of a cationic protein P: I 0.0100 0.0150 0.0200 0.0250 0.0300 0.0350 8.10 13.30 20.50 27.80 38.10 52.00 What can be deduced about the charge of P?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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