p + q = 1 (relative frequency/proportion of two different alleles in a population) p2 + 2pq + q2 = 1 (relative frequency/proportion of given genotypes in a population) p = frequency of the dominant allele in the population q = frequency of the recessive allele in the population p2 = percentage of homozygous dominant individuals q2 = percentage of homozygous recessive individuals 2pq = percentage of heterozygous individuals You have sampled a population of 10,599 individuals that you know is in Hardy-Weinberg equilibrium (HWE). The percentage of the homozygous recessive genotype (aa) is 36%. Using that 36%, calculate the following: a) The frequency of the "aa" genotype. b) The frequency of the "a" allele. c) The frequency of the "A" allele.

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p + q = 1 (relative frequency/proportion of two different alleles in a population)

p2 + 2pq + q2 = 1 (relative frequency/proportion of given genotypes in a population)

p = frequency of the dominant allele in the population
q = frequency of the recessive allele in the population
p2 = percentage of homozygous dominant individuals
q2 = percentage of homozygous recessive individuals
2pq = percentage of heterozygous individuals

  1. You have sampled a population of 10,599 individuals that you know is in Hardy-Weinberg equilibrium (HWE). The percentage of the homozygous recessive genotype (aa) is 36%. Using that 36%, calculate the following:
  2. a) The frequency of the "aa" genotype.
  3. b) The frequency of the "a" allele.
  4. c) The frequency of the "A" allele.
  5. d) The frequencies of the genotypes "AA" and "Aa."
  6. e) The frequencies of the two possible phenotypes if "A" is completely dominant over "a."
  7. f) How many of the individuals in this population show the dominant phenotype?
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