Over a period of two years, a man in his early 20s receiveda series of intermittent chemotherapy and radiotherapytreatments for Hodgkin disease. During this therapy, heand his wife were unable to initiate a pregnancy. The man had aseries of his semen samples examined at a fertility clinic. The findings revealed that shortly after each treatment very few mature sperm were present, and abnormal chromosome numbers were often observed in developing spermatocytes. However, such chromosome abnormalities disappeared about 40 days after treatment, and normal sperm reappeared about 74 days posttreatment. How might a genetic counselor explain the time-related differences in sperm production and the appearance and subsequent disappearance of chromosomal abnormalities?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Over a period of two years, a man in his early 20s received
a series of intermittent chemotherapy and radiotherapy
treatments for Hodgkin disease. During this therapy, he
and his wife were unable to initiate a pregnancy. The man had a
series of his semen samples examined at a fertility clinic. The findings revealed that shortly after each treatment very few mature sperm were present, and abnormal chromosome numbers were often observed in developing spermatocytes. However, such chromosome abnormalities disappeared about 40 days after treatment, and normal sperm reappeared about 74 days posttreatment.

How might a genetic counselor explain the time-related differences in sperm production and the appearance and subsequent disappearance of chromosomal abnormalities?

 

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