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| BRCA1 is a bi-allelic gene (let's call the two alleles as C and c) that is inherited on an autosome. The C allele is completely dominant over c, expressing breast cancer as a phenotype. Eye color is determined by two independently assorting bi-allelic genes, B (alleles B and b) and G (alleles G and g), such that the B allele shows dominant epistasis over the G and g alleles. Brown-eyed individuals have at least one copy of the B allele, green eyed individuals have at least one G allele, while blue eyed individuals have neither B nor G. A blue-eyed person whą is a heterozygote carrier for the BRCA1 gene has 3 children with a brown-eyed person (heterozygote for both B and G genes) who does not have breast cancer. (a) What are the possible genotypes and phenotypes of all their possible children? What are their respective probabilities of being observed (please write all genotype and phenotype probabilities)? (h) What is the probability that all three children will be blue-eyed and not have breast cancer?

| BRCA1 is a bi-allelic gene (let's call the two alleles as C and c) that is inherited on an autosome. The C allele is completely dominant over c, expressing breast cancer as a phenotype. Eye color is determined by two independently assorting bi-allelic genes, B (alleles B and b) and G (alleles G and g), such that the B allele shows dominant epistasis over the G and g alleles. Brown-eyed individuals have at least one copy of the B allele, green eyed individuals have at least one G allele, while blue eyed individuals have neither B nor G. A blue-eyed person whą is a heterozygote carrier for the BRCA1 gene has 3 children with a brown-eyed person (heterozygote for both B and G genes) who does not have breast cancer. (a) What are the possible genotypes and phenotypes of all their possible children? What are their respective probabilities of being observed (please write all genotype and phenotype probabilities)? (h) What is the probability that all three children will be blue-eyed and not have breast cancer?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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. BRCA1 is a bi-allelic gene (let's call the two alleles as C and c) that is inherited on an autosome. The C allele is completely dominant over c, expressing breast cancer as a phenotype. Eye color is determined by two independently assorting bi-allelic genes, B (alleles B and b) and G (alleles G and g), such that the Ballele shows dominant epistasis over the G and g alleles. Brown-eyed individuals have at least one copy of the B allele, green eyed individuals have at least one G allele, while blue eyed individuals have neither B nor G. A blue-eyed person whą is a heterozygote carrier for the BRCA1 gene has 3 children with a brown-eyed person (heterozygote for both B and G genes) who does not have breast cancer. (a) What are the possible genotypes and phenotypes of all their possible children? What are their respective probabilities of being observed (please write all genotype and phenotype probabilities)? (b) What is the probability that all three children will be blue-eyed and not have breast cancer?
Transcribed Image Text:. BRCA1 is a bi-allelic gene (let's call the two alleles as C and c) that is inherited on an autosome. The C allele is completely dominant over c, expressing breast cancer as a phenotype. Eye color is determined by two independently assorting bi-allelic genes, B (alleles B and b) and G (alleles G and g), such that the Ballele shows dominant epistasis over the G and g alleles. Brown-eyed individuals have at least one copy of the B allele, green eyed individuals have at least one G allele, while blue eyed individuals have neither B nor G. A blue-eyed person whą is a heterozygote carrier for the BRCA1 gene has 3 children with a brown-eyed person (heterozygote for both B and G genes) who does not have breast cancer. (a) What are the possible genotypes and phenotypes of all their possible children? What are their respective probabilities of being observed (please write all genotype and phenotype probabilities)? (b) What is the probability that all three children will be blue-eyed and not have breast cancer?
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