One of the tests for coronavirus relies on reverse transcriptase. Explain how you might mass produce reverse transcriptase through a method similar to how we mass produce human insulin.
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One of the tests for coronavirus relies on reverse transcriptase. Explain how you might mass produce reverse transcriptase through a method similar to how we mass produce human insulin.
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- A number of retroviruses can infect certain human cells. List two of them, briefly describe the medical implications resulting from these infections, and describe why only certain cells are infected.Reverse transcriptase is an error prone DNA polymerase. Describe the role of reverse transcriptase in viral propagation and how having an error-prone enzyme might make it challenging to have a vaccineAnswer the following 1.Are viruses living or non-living organisms? 2. What is the difference between HIV and AIDS? 3. HIV is classified as a retrovirus. What are retroviruses? 4. In your own words, provide a short summary of the HIV replication cycle. 5. Why is reverse transcriptase an important enzyme in the replication cycle of HIV? 6. In the chapter about enzymes, we have discussed how drugs are basically inhibitors. There are currently a multitude of Antiretroviral therapy (ART or ARV) options available to people living with HIV (PLHIV) so that the viral replication is suppressed and does not progress to AIDS. What do you think these drugs target? Discuss briefly. 7. SARS-CoV-2, the virus that causes CoVid-19, belongs to the Coronaviridae family. Viruses under this family have a genome made of single-stranded positive-sense RNA. Is this similar to the viral genome of HIV? If so, do you think that – in theory – they would have similar replication cycles? 8. In your own opinion, do…
- Explain the role of RNase H (a component of reverse transcriptase)during the synthesis of HIV DNA.Explain the patenting of the Biontech vaccine, the studies carried out at the university, how this vaccine was found and with which institutions it was studied, explain all the processes of the discovery of the vaccine (Please don't give a short answer)Include the steps in the correct order from attachment to lysis. How does this differ from the virus replication cycle in animals? Explain the difference between lytic cycle, lysogeny and slow release. Also include the bacterial defense mechanism bacteria have developed to prevent infection by a virus. How is this bacterial defense now being used to modify genetic codes in humans, include CRISPR in your discussion. Explain the growth curve of a virus and what phase is the coronal virus in the present pandemic?
- Answer the following and inlcude the references SARS-CoV-2, the virus that causes CoVid-19, belongs to the Coronaviridae family. Viruses under this family have a genome made of single-stranded positive-sense RNA. Is this similar to the viral genome of HIV? If so, do you think that – in theory – they would have similar replication cycles? Do you think that ART combinations/options might help in suppressing the viral replication of SARS-CoV-2? Expound.Simian Virus 40 is carcinogenic in primates. 1). which molecule of the virus 2). what particular property of the molecule that enable the malignant transformation.Retroviruses can sometimes increase the likelihood of developing cancer. There are two ways that this can happen. Describe these two ways. 
- Why can protease inhibitors and nucleoside analogs be used in minimizing the replication of the HIV virus?Explain that a virus can’t be treated with an antibiotic and why. Think about selective toxicity and why those targets don’t exist for a viral infection.An antimicrobial drug binds to the HIV reverse transcriptase enzyme, preventing it from working. Which of the following is true of this drug? It would inhibit early replication steps of some viruses, but not affect normal eukaryotic cell activity. It would directly interfere with translation of some viral proteins and some eukaryotic proteins. It would block assembly/maturation steps of some viruses, and interfere with translation in eukaryotic cells. It would interfere with release of newly formed viruses from a host cell, but not affect eukaryotic cells. It would interfere with protein synthesis in bacteria, but not affect eukaryotic ribosomes. It would interfere with mRNA transcription in bacteria and viruses, but not affect eukaryotic transcription.