One of the common unfortunate consequences of a vasectomy is that the proximal ends of the ductus deferens rupture and spermatozoa are exposed to the immune system. The person with the testes then produces antibodies against their own sperm. This has consequences for the effectiveness of a vasectomy reversal.   In the situation described above, why are the spermatozoa considered foreign even though they are being produced within the person’s own seminiferous tubules? This immune response is not normal, and so describe how the testes’ structure prevents this immune reaction from occurring.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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  1. One of the common unfortunate consequences of a vasectomy is that the proximal ends of the ductus deferens rupture and spermatozoa are exposed to the immune system. The person with the testes then produces antibodies against their own sperm. This has consequences for the effectiveness of a vasectomy reversal.

 

In the situation described above, why are the spermatozoa considered foreign even though they are being produced within the person’s own seminiferous tubules? This immune response is not normal, and so describe how the testes’ structure prevents this immune reaction from occurring.

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