One model of the glomerular membrane is a microporous membrane in which right cylindrical pores penetrate all the way through the membrane. Assume that the pores have a length of 50 nm and a radius of 3.5 nm. The viscosity of plasma is 0.002 Pa s. The average hydrostatic pressure in the glomerulus is 60 mm Hg, hydrostatic pressure in Bowman's space is 20 mm Hg and the average oncotic pressure of glomerular capillary blood is 28 mm Hg. A. Calculate the flow through a single pore assuming laminar flow (use the Poiseuille flow equation) B. How many pores would there have to be to produce a normal GFR? C. If the total aggregate area of the kidneys for filtration is 1.5 m2, what is the density of the pores (number of pores per unit area)? D. What fraction of the area is present as pores? 4) One model of the glomerular membrane is a microporous membrane in which right cylindricalpores penetrate all the way through the membrane. Assume that the pores have a length of 50 nmand a radius of 3.5 nm. The viscosity of plasma is 0.002 Pa s. The average hydrostatic pressure inthe glomerulus is 60 mm Hg, hydrostatic pressure in Bowman's space is 20 mm Hg and the averageoncotic pressure of glomerular capillary blood is 28 mm Hg.A. Calculate the flow through a single pore assuming laminar flow (use the Poiseuille flowequation).B. How many pores would there have to be to produce a normal GFR?C. If the total aggregate area of the kidneys for filtration is 1.5 m², what is the density of the pores(number of pores per unit area)?D. What fraction of the area is present as pores?

The glomerular filtration surface will consist of endothelial pores, glomerular basement membrane,…

Answered: One model of the glomerular membrane is…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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One model of the glomerular membrane is a microporous membrane in which right cylindrical pores penetrate all the way through the membrane. Assume that the pores have a length of 50 nm and a radius of 3.5 nm. The viscosity of plasma is 0.002 Pa s. The average hydrostatic pressure in the glomerulus is 60 mm Hg, hydrostatic pressure in Bowman's space is 20 mm Hg and the average oncotic pressure of glomerular capillary blood is 28 mm Hg. A. Calculate the flow through a single pore assuming laminar flow (use the Poiseuille flow equation) B. How many pores would there have to be to produce a normal GFR? C. If the total aggregate area of the kidneys for filtration is 1.5 m2, what is the density of the pores (number of pores per unit area)? D. What fraction of the area is present as pores?