One challenge when reacting the enolate of acetone with an alkyl halide (R-X) is avoiding an alternative reaction pathway that involves: (3 pts)i)Decarboxylation of the product ii) Dehydration - elimination of the beta -hydroxyketone product ii) Elimination of the alkyl halide iv) 1,2 vs 1,4-addition

Step 1: Step 2: Step 3: Step 4:

Answered: One challenge when reacting the enolate…

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Propose a structure for the starting material of the below reaction scheme, and answer any follow-up questions. Answer with the number of the correct starting material (i.e. 1, 2, 3, 4, 5, or 6) 1 4 1.0₂ 2. DMS GẠOOCH + 2 CHỊ CHO + 5 What is the name of the reagent used in step 2 of the reaction? OHCCH₂CH(CH₂COOH to Je 3 6 hen ozone attacks a double or triple bond, what is the name of the initial intermediate formed? hp
Q8. How would you carry out the following conversions? Show the pathway using correct chemical formula of each compound and condition required for the conversion. [3x2=6] i) ii) Acetaldehyde to Hemiacetal Hemiketal to Ketal iii) Acetal to Acetaldehyde
Choose the reagent(s) from the list at right and give the number of equivalents required. Draw out the R group of the reagent needed. Draw the by-products of the reaction. 26. 27. H C-C Bond Forming Reagents: 1) R-MgBr 2) H3O*CH 1) R-Li 2) H₂O*CI 1) R-CH₂X, PPh3, 2) n-BuLi 1) (EtO)2P(=O)CH₂EWG, 2) NaH CO₂Et
42 Draw the hemiacetal and then the acetal formed in each reaction. In each case, assume an excess of the alcohol. (D) 12 (a) Propanal+ methanol → (b) Cyclopentanone + methanol- Drow the at
mixed Claisen condensation of methyl benzoate with methyl propanoate 1 gives * 3-ethyl-2-methyl-3-oxo-3-phenylpropanoate O ethyl-2-methyl-3-oxo-3-phenylpropanoate O Methyl-2-methyl-3-oxo-3-phenylpropanoate 3-Methyl-2-methyl-3-oxo-3-phenylpropanoate Micheal reaction of 2-methyl-1,3-cyclohexanedione with methylvinylketone 1 2-methyl-2-(3-oxobutyl)-1,3-cyclohexanedion 4-methyl-2-(3-oxobutyl)-1,3-cyclohexanedion 3-methyl-2-(3-oxobutyl)-1,3-cyclohexanedion
! 11:50 %0AONO propanoic acid can be prepared from reaction with EtONa, CH3-Br And H3O+, heat / -CO2 diethyl malonate ethyl acetoacetate diethyl acetate ethyl acetate i CH₂ a) CH₂-C-PPh a d b) CH₂-C-P CH₂ CH₂-C-C-CH₂ CH₂ CH₂ CH, CH CH₂ O d) CH₂ CH₂ CH₂ C-Phy CH₂
What is the mechanisms to get from the reactant to the products
Aa.92.
1. For the carbonyl compounds shown below, identify those that are best suited for nucleophilic addition reactions and those that are cable of nucleophilic substitution reactions. لو لايلو لي على I I II I 2. Which carbonyl compound would react the fastest during a nucleophilic substitution reaction? (3 pts) 0 II I III COOH III II 3. Which carbonyl compound would react the slowest during a nucleophilic substitution reaction? ( 4. Rank the following compounds in order of increasing acidity OH COOH IV - NO2 IV لي للبلابل III IV *NH2 V CH3 V *NHz V NH₂ COOH IV مي OH Br

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