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- la . Rank the following substrates from most (1) to least reactive (3) in an Sn2 reaction. Explain the reason for your choice Br Br Br В A lb. Rank the following substrates from most (1) to least reactive (4) in an SN1 reaction. Explain the reason for your choice Br Br Br Br A B C Dneed help4. Rank the following leaving groups from best to worst. LOH, -CH3 -NH2 LG LG LG LG LG A B C D E
- Draw the major organic product for each of the hydroboration-oxidation reactions. Disregard stereochemistry. Draw the product of Reaction A. Select Draw Rings More ||||||CH|OB Reaction A. 1. B₂H6 2. H₂O₂ (aq) 3M NaOH Reaction B. 1. B₂H6 2. H₂O₂ (aq) 3M NaOH S 3 Draw the product in reaction B. Select Draw Rings More |||||||||CH|OB Erase Q2Q Erase Q2Q6). What is the major product of the following reactions? (A) -? coon 1). NaOH in ErOH, then H,O+ 2). 1 eqiv. NaOEt 3). 1 equiv. CH3Br 4). H₂O*, Heat COOB (Intramolecular Claison) COOE (B) CH₂ COOH (D) CH₂ (E) CH3 CH₂Draw the major nucleophilic substitution product of each reaction below, showing stereochemistry when necessary. Circle which mechanism type, SNl or SN2, each reaction proceeds by. You do not need to show the mechanisms. CI Но- Syl or SN2 a. Br Snl NANH2 or Sy2 b. DMSO SN1 O Na or Br Acetone Sy2 с.
- Identify the sequence of reactions that successfully completes the following transformation. Ph A. 1. BH3 2. H₂O₂ / NaOH _3. P, l₂ B. HI, ROOR, hv C. 1. HBr, ROOR, hv 2. Nal, acetone D. Choices A and C Phc) Complete the following reaction scheme for structures E, F, G, H and I. F Br2 / H20 Cl i. BH3, THF ii. H2O2 / H* КОН E G i. Оз ii. (CH3)2S H + IWrite out the expected splitting pattern for hydrogens Ha, Hp and Hc 3Jab = 10 Hz На Hb 3Jpc = 7 Hz CI Hc Hc Ha:Hb:Hc: doublet, quartet, doublet Ha:Hb:Hc: quartet, quartet, triplet Ha:Hb:Hc: doublet, doublet of triplets, doublet Ha:Hb:Hc: doublet, triplet of doublets, doublet
- 3. Show a plausible mechanism for the reaction below. , NH2 ELOH, cat. HCI CH H,C- CH NH, CH1. Give the major product(s) of the following reactions as needed. Include any stereoisomers. NaOEt 1. Br NaOH Br 2. NaOtBu 3. A MEOH 4. Br 2. Which reaction will proceed faster A or B? H,S H2S "CI .... вGive the major organic product of the following reactions (a-e).