Oct 16 4. At least 4 different typical electrophiles (contributing 5 C's, 6 C's, or 7 C's), when reacted with the proper nucleophiles, can be used to make a C-C bond leading directly to the target below (after H3O'). Show two different pairs of nucleophile and electrophile you can combine to make the target directly. You may show up to four pairs, and I will count your best two. Nucleophile + Electrophile OH (3-ethyl-3-heptanol) Nucleophile + Electrophile

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**Nucleophiles and Electrophiles in Organic Synthesis**

In this exercise, you are tasked with applying your knowledge of nucleophiles and electrophiles to synthesize a specific target molecule, 3-ethyl-3-heptanol. 

**Objective:**
Identify at least four different typical electrophiles, each contributing either 5, 6, or 7 carbon atoms. These electrophiles, when reacted with appropriate nucleophiles, can form a carbon-carbon bond leading directly to 3-ethyl-3-heptanol. You will need to show two different pairs of nucleophiles and electrophiles that can be combined to achieve the target. You can present up to four pairs, and your best two will be evaluated.

**Diagram Explanation:**
The diagram illustrates the reaction pathway leading to 3-ethyl-3-heptanol. 
- On the left, several boxes labeled "Nucleophile + Electrophile" suggest multiple potential pairings.
- An arrow points from these boxes to the structure of the target molecule, 3-ethyl-3-heptanol.
- A symmetrical arrangement is shown, indicating that there is more than one nucleophile-electrophile pairing to achieve this synthesis.

**Assignment:**
Demonstrate your understanding of nucleophiles and electrophiles by:
1. Selecting appropriate electrophiles based on the carbon count requirements.
2. Identifying suitable nucleophiles that will effectively pair with your chosen electrophiles.
3. Illustrating the reaction mechanism for each pair to show how they lead to the formation of the target molecule.

Your ability to identify and justify the usage of different electrophile and nucleophile combinations will reflect your mastery in synthetic organic chemistry. This exercise not only enhances your problem-solving skills but also prepares you for more complex synthesis challenges.
Transcribed Image Text:**Nucleophiles and Electrophiles in Organic Synthesis** In this exercise, you are tasked with applying your knowledge of nucleophiles and electrophiles to synthesize a specific target molecule, 3-ethyl-3-heptanol. **Objective:** Identify at least four different typical electrophiles, each contributing either 5, 6, or 7 carbon atoms. These electrophiles, when reacted with appropriate nucleophiles, can form a carbon-carbon bond leading directly to 3-ethyl-3-heptanol. You will need to show two different pairs of nucleophiles and electrophiles that can be combined to achieve the target. You can present up to four pairs, and your best two will be evaluated. **Diagram Explanation:** The diagram illustrates the reaction pathway leading to 3-ethyl-3-heptanol. - On the left, several boxes labeled "Nucleophile + Electrophile" suggest multiple potential pairings. - An arrow points from these boxes to the structure of the target molecule, 3-ethyl-3-heptanol. - A symmetrical arrangement is shown, indicating that there is more than one nucleophile-electrophile pairing to achieve this synthesis. **Assignment:** Demonstrate your understanding of nucleophiles and electrophiles by: 1. Selecting appropriate electrophiles based on the carbon count requirements. 2. Identifying suitable nucleophiles that will effectively pair with your chosen electrophiles. 3. Illustrating the reaction mechanism for each pair to show how they lead to the formation of the target molecule. Your ability to identify and justify the usage of different electrophile and nucleophile combinations will reflect your mastery in synthetic organic chemistry. This exercise not only enhances your problem-solving skills but also prepares you for more complex synthesis challenges.
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