Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
The conversion of acetyl chloride to methyl acetate occurs via the following two-step mechanism:
a.Add curved arrows to show the movement of the electrons in each step.
b.Write the rate equation for this reaction, assuming the first step is ratedetermining.
c.If the concentration of −OCH3 were increased 10 times, what would happen to the
d.If the concentrations of both CH3COCl and −OCH3 were increased 10 times, what would happen to the rate of the reaction?
e.Classify the conversion of acetyl chloride to methyl acetate as an addition, elimination, or substitution.
![:O:
:ö: :OCH3
:O:
[1]
[2]
ÖCH3
slow
Ci:
fast
ӦСНЗ
acetyi chloride
methyl acetate](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F5a040f5b-68a7-42c7-951d-b2c2f55f1248%2F2b626cf8-0194-4a39-a9ad-abc490023939%2F80ekhbg.png&w=3840&q=75)
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