Now use the equations above and the empirical values below to calculate VO₂ (the rate of oxygen consumption). Be sure to show your calculations, including the units. Check that the units are right (it's easier than it might seem). VEATPS = 53.7 L Time interval= 1 min Pb=767 mm Hg PH20= 19.8 mm Hg T₁ = 22°C FEO₂=0.163

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Assume that you have measured heart rate, ventilation rate and volume, oxygen consumption,
and carbon dioxide production during exercise. In principle, the rate of oxygen consumption
(VO2) reflects the difference in oxygen between inspired air and expired air; note that for
simplicity, V here refers to rate (and should have a dot over it) and not volume. The volume of
oxygen consumed equals the volume of air times the percent of air comprised of oxygen. The
rate of oxygen consumption takes time into account.
However, because temperature, pressure, and water vapor affect air volumes, measured air
volumes are not all comparable to one another; to be comparable, they need to be corrected to a
common set of conditions, such as STPD (standard temperature and pressure, dry). In simplified
form, the equation for oxygen consumption is:
VO2 = VESTPD (FIO2 - FEO2)
where VE = the rate of expired air (volume/time), FIO₂ = fractional concentration of inspired
oxygen, and FEO2 = fractional concentration of expired oxygen. FIO2 is constant in outside air
(approximately 0.2093). So:
VO2 = VESTPD (0.2093 - FEO2).
The formula for correcting VE to STPD is:
VESTPD = (VEATPS / time) × ((Pb-PH20)/760) × (273/(273+ Ta))
where VEATPS is the volume of expired air saturated and at ambient temperature and pressure, Pb
is the barometric pressure, PH20 is the saturated water vapor pressure, 760 is the designated
standard pressure (in mm Hg), 273 is degrees K, and Ta is ambient temperature in degrees C.
Units are not shown here for simplicity.
From these equations for VO2, it should be apparent that oxygen consumption is dependent
on ventilation rate (VE) and oxygen extraction by the lungs (FIO2 - FEO2).
Now use the equations above and the empirical values below to calculate VO₂ (the rate of
oxygen consumption). Be sure to show your calculations, including the units. Check that the
units are right (it's easier than it might seem).
VEATPS = 53.7 L
Time interval = 1 min
Pb = 767 mm Hg
PH20 19.8 mm Hg
Ta = 22°C
FEO₂ = 0.163
Transcribed Image Text:Assume that you have measured heart rate, ventilation rate and volume, oxygen consumption, and carbon dioxide production during exercise. In principle, the rate of oxygen consumption (VO2) reflects the difference in oxygen between inspired air and expired air; note that for simplicity, V here refers to rate (and should have a dot over it) and not volume. The volume of oxygen consumed equals the volume of air times the percent of air comprised of oxygen. The rate of oxygen consumption takes time into account. However, because temperature, pressure, and water vapor affect air volumes, measured air volumes are not all comparable to one another; to be comparable, they need to be corrected to a common set of conditions, such as STPD (standard temperature and pressure, dry). In simplified form, the equation for oxygen consumption is: VO2 = VESTPD (FIO2 - FEO2) where VE = the rate of expired air (volume/time), FIO₂ = fractional concentration of inspired oxygen, and FEO2 = fractional concentration of expired oxygen. FIO2 is constant in outside air (approximately 0.2093). So: VO2 = VESTPD (0.2093 - FEO2). The formula for correcting VE to STPD is: VESTPD = (VEATPS / time) × ((Pb-PH20)/760) × (273/(273+ Ta)) where VEATPS is the volume of expired air saturated and at ambient temperature and pressure, Pb is the barometric pressure, PH20 is the saturated water vapor pressure, 760 is the designated standard pressure (in mm Hg), 273 is degrees K, and Ta is ambient temperature in degrees C. Units are not shown here for simplicity. From these equations for VO2, it should be apparent that oxygen consumption is dependent on ventilation rate (VE) and oxygen extraction by the lungs (FIO2 - FEO2). Now use the equations above and the empirical values below to calculate VO₂ (the rate of oxygen consumption). Be sure to show your calculations, including the units. Check that the units are right (it's easier than it might seem). VEATPS = 53.7 L Time interval = 1 min Pb = 767 mm Hg PH20 19.8 mm Hg Ta = 22°C FEO₂ = 0.163
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