NEt HO. HNE + Br NH, (a) (b) (c) (d) proparcaine EIOH, H* (a) NaOH, Ф), HNO,, H,SO, (1), H* H2. Pt H,O proparcaine (c) + (d) The anesthetic, proparcaine, can be synthesized from these simple precursors. Work out the synthesis on a separate sheet of paper, and then draw the structure of (e). • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading. • Draw the Grignard reagent as a covalent magnesium bromide.

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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HO.
Br
HNE
+
NH,
(a)
(b)
(c)
(d)
proparcaine
EIOH, H*
(a)
HNO,, H,SO,
NaOH, (b)
H,O'
(1). H*
Hy. Pt
(e)
proparcaine
(c) + (d)
The anesthetic, proparcaine, can be synthesized from these simple precursors.
Work out the synthesis on a separate sheet of paper, and then draw the structure of (e).
• You do not have to consider stereochemistry.
• You do not have to explicitly draw H atoms.
• Do not include lone pairs in your answer. They will not be considered in the grading.
• Draw the Grignard reagent as a covalent magnesium bromide.
opy aste
Pr
Transcribed Image Text:HO. Br HNE + NH, (a) (b) (c) (d) proparcaine EIOH, H* (a) HNO,, H,SO, NaOH, (b) H,O' (1). H* Hy. Pt (e) proparcaine (c) + (d) The anesthetic, proparcaine, can be synthesized from these simple precursors. Work out the synthesis on a separate sheet of paper, and then draw the structure of (e). • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading. • Draw the Grignard reagent as a covalent magnesium bromide. opy aste Pr
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