n the Physician’s Health Study, 22,071 male physicians participated in a study to determine whether taking a daily low-dose aspirin reduced the risk of heart attacks. The men were randomly assigned to two groups and the study was double-blind. After five years, 104 of the 11,037 men taking a daily low dose aspirin had had a heart attack while 189 of the 11,034 men taking a placebo had had a heart attack.1 Does taking a daily low-dose aspirin reduce the risk of heart attacks? 1‘‘Final report on the aspirin component of the ongoing Physicians’ Health Study. Steering Committee of the Physicians’ Health Study Research Group”, New England Journal of Medicine, 1989 Jul 20; 321(3): 129-135. (a) State the null and alternative hypotheses. Your answer should be an expression composed of symbols: =,≠,<,>,μ,μ1,μ2,p,p1,p2,ρ,p^,p^1,p^2,r. Use subscripts 1 for the treatment group (taking the daily low-dose aspirin) and 2 for the control group (taking a placebo). H0: vs Ha:Edit (b) Give the test statistic and the p-value. Round your intermediate results to four decimal places. Round your answer for the test statistic to two decimal places and your answer for the p-value to three decimal places. test statistic = Enter your answer in accordance to item (b) of the question statement p-value = Enter your answer in accordance to item (b) of the question statement What is the conclusion? Choose the answer from the menu in accordance to item (b) of the question statement H0. (c) Does taking a daily low-dose aspirin reduce the risk of heart attacks? Yes No (d) Why can we infer a causal relationship from the results? Because the p-value is so low Because the p-value is so high Because the results are significant and the results come from an experiment Because the results are significant and the results come from an observational study
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