n the genetically inherited disease called hemophilia. From the information in he pedigree chart (right), answer the following questions: Hemophilia in humans a) If 112 marries a normal man, what is the probability of her first child being a hemophiliac? 1 2 b) Suppose her first child is actually a hemophiliac. What is the chance that her second child will be a boy with hemophilia? 2 3 c) If 114 has children with a hemophiliac man, what is the probability that her first child will be phenotypically normal? d) If the mother of 12 was phenotypically normal, what phenotype was her father?

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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3. The recessive sex-linked gene (h) prolongs the blood-clotting time, resulting
in the genetically inherited disease called hemophilia. From the information in
the pedigree chart (right), answer the following questions:
Hemophilia in humans
(a) If 112 marries a normal man, what is the probability of her first child being
a hemophiliac?
2
(b) Suppose her first child is actually a hemophiliac. What is the chance that
her second child will be a boy with hemophilia?
2
(c) If I14 has children with a hemophiliac man, what is the probability that her first child will be phenotypically normal?
(d) If the mother of 12 was phenotypically normal, what phenotype was her father?
4. The phenotypic expression of a dominant gene in
Ayrshire cattle is a notch in the tips of the ears. In
the pedigree chart on the right, notched animals are
represented by the solid symbols.
Ear notches in Ayrshire cattle
Determine the probability of notched offspring being
produced from the following matings:
1
2
(a) III1 x III3
II
(b) III3 x III2
(c) II13 x II14
(d) III1 x III5
Transcribed Image Text:3. The recessive sex-linked gene (h) prolongs the blood-clotting time, resulting in the genetically inherited disease called hemophilia. From the information in the pedigree chart (right), answer the following questions: Hemophilia in humans (a) If 112 marries a normal man, what is the probability of her first child being a hemophiliac? 2 (b) Suppose her first child is actually a hemophiliac. What is the chance that her second child will be a boy with hemophilia? 2 (c) If I14 has children with a hemophiliac man, what is the probability that her first child will be phenotypically normal? (d) If the mother of 12 was phenotypically normal, what phenotype was her father? 4. The phenotypic expression of a dominant gene in Ayrshire cattle is a notch in the tips of the ears. In the pedigree chart on the right, notched animals are represented by the solid symbols. Ear notches in Ayrshire cattle Determine the probability of notched offspring being produced from the following matings: 1 2 (a) III1 x III3 II (b) III3 x III2 (c) II13 x II14 (d) III1 x III5
Expert Solution
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Haemophilia follows X linked recessive pattern. The genes associated with this condition are located on the X chromosome, which is one of the two sex chromosomes. In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition

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