Method DNAS sensitivity to DNase I was tested on different tissues and at different times in development. Key DNA highly sensitive to DNase I Embryonic globin gene globin genes Adult Chicken DNA U aD Results Erythroblasts first 24 hours Before hemoglobin synthesis, none of the globin genes are sensitive to DNase I digestion. a4 After globin synthesis has begun, all genes are sensitive to DNase I, but the embryonic globin gene Uis the most sensitive. Erythroblasts 5 days In the 14-day-old embryo, when only adult hemoglobin is expressed, adult genes are most sensitive and the embryonic gene is insensitive. Erythroblasts 14 days Globin genes in the brain- which does not produce globin-remain insensitive throughout development. Brain cells throughout development Conclusion: Sensitivity of DNA to digestion by DNase I is correlated with gene expression, suggesting that chromatin structure changes in the course of transcription. DNase I sensitivity is correlated with the transcription of globin genes in chick embryos.
DNA and RNA
Deoxyribonucleic acid (DNA) is usually called the blueprint of life. Deoxyribose is a monosaccharide that has a key function in the synthesis of deoxyribonucleic acid. One less oxygen-containing hydroxyl group occurs in deoxyribose sugar. Nucleic acid, deoxyribonucleic acid, is one of the natural components. Deoxyribonucleic acid is a double-stranded molecule. Watson and Crick postulated the double-stranded model of the helix. A deoxyribonucleic acid is a molecular group that carries and transmits genetic information from parents to offspring. All eukaryotic and prokaryotic cells are involved.
DNA as the Genetic Material
DNA, or deoxyribonucleic acid, is a long polymeric nucleic acid molecule discovered in the late 1930s. It is a polymer; a long chain-like molecule made up of several monomers connected in a sequence. It possesses certain characteristics that qualify it as a genetic component. Certain organisms have different types of nucleic acids as their genetic material - DNA or RNA.
Genetics
The significant branch in science which involves the study of genes, gene variations, and the organism's heredity is known as genetics. It is also used to study the involvement of a gene or set of genes in the health of an individual and how it prevents several diseases in a human being. Thus, genetics also creates an understanding of various medical conditions.
DNA Replication
The mechanism by which deoxyribonucleic acid (DNA) is capable of producing an exact copy of its own is defined as DNA replication. The DNA molecules utilize a semiconservative method for replication.
Based on the sensitivity of DNA to DNase I, as illustrated in Figure , which type of chicken hemoglobin (embryonic or adult) is likely to be produced in the highest quantity in the following tissues and developmental stages?
Q. Brain cells throughout development
![Method DNAS sensitivity to DNase I was tested on different
tissues and at different times in development.
Key
DNA highly
sensitive
to DNase I
Embryonic
globin gene globin genes
Adult
Chicken
DNA
U aD
Results Erythroblasts
first 24 hours
Before hemoglobin synthesis,
none of the globin genes are
sensitive to DNase I digestion.
a4
After globin synthesis has
begun, all genes are sensitive
to DNase I, but the embryonic
globin gene Uis the most
sensitive.
Erythroblasts
5 days
In the 14-day-old embryo,
when only adult hemoglobin
is expressed, adult genes are
most sensitive and the
embryonic gene is insensitive.
Erythroblasts
14 days
Globin genes in the brain-
which does not produce
globin-remain insensitive
throughout development.
Brain cells
throughout
development
Conclusion: Sensitivity of DNA to digestion by DNase I is correlated with gene expression,
suggesting that chromatin structure changes in the course of transcription.
DNase I sensitivity is correlated with the transcription of globin genes
in chick embryos.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fac905c84-e770-4b5b-a67a-0cfc6dac8e02%2F447f0d46-e7ab-4fc5-80ad-6f969f25a586%2Fmco3d07.jpeg&w=3840&q=75)
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