Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of Keg and Q, the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP Calculate K, for this reaction at T = 25.0 °C. AG' = -14.2 kJ/mol Ka %3D Calculate the mass-action ratio, Q , from the approximate physiological concentrations for rat heart tissue shown in the table. Metabolite Concentration (µM) Q = fructose 6-phosphate fructose 1,6-bisphosphate 84.0 29.0 ATP 11,800 ADP 1,310

Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of Keg and Q, the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP Calculate K, for this reaction at T = 25.0 °C. AG' = -14.2 kJ/mol Ka %3D Calculate the mass-action ratio, Q , from the approximate physiological concentrations for rat heart tissue shown in the table. Metabolite Concentration (µM) Q = fructose 6-phosphate fructose 1,6-bisphosphate 84.0 29.0 ATP 11,800 ADP 1,310

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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A chemist fills a reaction vessel with 0.328 g silver chromate (Ag₂ CrO4) solid, 0.724 M silver (Ag*) aqueous solution, and 0.106 M chromate (CrO 2- Cro₂²-) 4 aqueous solution at a temperature of 25.0°C. Under these conditions, calculate the reaction free energy AG for the following chemical reaction: 2- Ag₂ CrO4(s) 2 Ag+ (aq) + CrO₂ (aq) Use the thermodynamic information in the ALEKS Data tab. Round your answer to the nearest kilojoule. เม kJ X
With little explanation
Actual free-energy change is a function of the reactant and product concentrations and the temperature at which the reaction occurs. AG = Go + RT In Use the equation for the actual free-energy change to plot AG against In Q at 25 °C for the five concentrations of ATP, ADP, and P₁ shown in the table. The AG' for the reaction is -30.5 kJ/mol. Concentration (mm) 0.2 5.0 14.9 O O AG (kJ/mol) Metabolite ATP ADP P₁ Select the graph that plots the data. AG (kJ/mol) 0 -20 -40 -~ 0 200 0 -200 [C]c[D]d [A]a[B]b -400 T 2 5 0.2 10 2 T 4 3 2.2 12.1 InQ 6 4 InQ 6 8 1 4.2 14.1 10 8 5 25 10 AG (kJ/mol) AG (kJ/mol) 0 -20 -40 -10 -8 0 -20 -40 -6 -4 InQ -2 0
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The standard free energy change for the hydrolysis of ATP is -30.5 kJ ATP(aq)+H₂O(1)→ADP(aq) +Pi(aq) In a particular cell, the concentrations of ATP, ADP, and Pi are 0.0031 M, 0.0015 M, and 0.0048 M, respectively. Calculate the free energy change for the hydrolysis of ATP under these conditions. (Assume a temperature of 298 K.)
The equilibrium constant, Kc, for the following reaction is 14.9 at 332 K.2CH2Cl2(g) CH4(g) + CCl4(g)Calculate Kc at this temperature for:CH4(g) + CCl4(g) 2CH2Cl2(g) Kc=
A chemist fills a reaction vessel with 3.93 atm methane (CH,) gas, 1.61 atm oxygen (O,) gas, 5.89 atm carbon dioxide (CO,) gas, and 4.78 atm hydrogen (H2) gas at a temperature of 25.0°C. Under these conditions, calculate the reaction free energy AG for the following chemical reaction: CH, (g) +0,(g) CO,(g)+2H, (g) Use the thermodynamic information in the ALEKS Data tab. Round your answer to the nearest kilojoule. || kJ