Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of Kéq and Q, the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP Calculate Ke, for this reaction at T = 25.0 °C. AG' = -14.2 kJ/mol Calculate the mass-action ratio, Q, from the approximate physiological concentrations for rat heart tissue shown in the table. Metabolite Concentration (µM) Q = fructose 6-phosphate 84.0 fructose 1,6-bisphosphate 25.0 АТР 12,100 ADP 1,280 Select the true statements about the PFK-1 reaction. The PFK-1 reaction in heart tissue does not reach equilibrium. In heart tissue, the PFK-1 reaction will be driven toward product formation. In heart tissue, the PFK-1 products are more abundant than reactants. Under standard conditions, the PFK-1 reaction reaches equilibrium when the concentrations of all products and reactants are equal.
Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of Kéq and Q, the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP Calculate Ke, for this reaction at T = 25.0 °C. AG' = -14.2 kJ/mol Calculate the mass-action ratio, Q, from the approximate physiological concentrations for rat heart tissue shown in the table. Metabolite Concentration (µM) Q = fructose 6-phosphate 84.0 fructose 1,6-bisphosphate 25.0 АТР 12,100 ADP 1,280 Select the true statements about the PFK-1 reaction. The PFK-1 reaction in heart tissue does not reach equilibrium. In heart tissue, the PFK-1 reaction will be driven toward product formation. In heart tissue, the PFK-1 products are more abundant than reactants. Under standard conditions, the PFK-1 reaction reaches equilibrium when the concentrations of all products and reactants are equal.
Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of Kéq and Q, the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP Calculate Ke, for this reaction at T = 25.0 °C. AG' = -14.2 kJ/mol Calculate the mass-action ratio, Q, from the approximate physiological concentrations for rat heart tissue shown in the table. Metabolite Concentration (µM) Q = fructose 6-phosphate 84.0 fructose 1,6-bisphosphate 25.0 АТР 12,100 ADP 1,280 Select the true statements about the PFK-1 reaction. The PFK-1 reaction in heart tissue does not reach equilibrium. In heart tissue, the PFK-1 reaction will be driven toward product formation. In heart tissue, the PFK-1 products are more abundant than reactants. Under standard conditions, the PFK-1 reaction reaches equilibrium when the concentrations of all products and reactants are equal.
Many metabolites are maintained at steady‑state concentrations that are far from equilibrium. A comparison of ?′eq and ? , the mass‑action ratio, can determine whether a metabolic reaction is far from equilibrium...
Transcribed Image Text:Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of Kg and Q,
the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium.
The equation for this equilibrium is,
fructose 6-phosphate + ATP = fructose 1,6-bisphosphate + ADP
Calculate Kea for this reaction at T = 25.0 °C.
AG'
-14.2 kJ/mol
Keg =
Calculate the mass-action ratio, Q , from the approximate physiological concentrations for rat heart tissue shown in the table.
Metabolite
Concentration (µM)
fructose 6-phosphate
84.0
fructose 1,6-bisphosphate
25.0
ATP
12,100
ADP
1,280
Select the true statements about the PFK-1 reaction.
The PFK-1 reaction in heart tissue does not reach equilibrium.
In heart tissue, the PFK-1 reaction will be driven toward product formation.
In heart tissue, the PFK-1 products are more abundant than reactants.
Under standard conditions, the PFK-1 reaction reaches equilibrium when the concentrations of all products and reactants
are equal.
II
Chemical pathways by which living things function, especially those that provide cellular energy, such as the transformation of energy from food into the energy of ATP. Metabolism also focuses on chemical pathways involving the synthesis of new biomolecules and the elimination of waste.
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