Aconitase catalyzes the reversible isomerization of citrate to isocitrate. CH,CO0 CH,Co0 HO-C-coo H-C-co0" H- -co0" HO-C-cOo H. citrate isocitrate Determine uhi

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
Question
Aconitase catalyzes the reversible isomerization of citrate to isocitrate.
CH,CO0
CH,CO0
HO-C-co0
H-
H-C-coo"
HO-C-coo
citrate
isocitrate
Determine which statements regarding aconitase are true.
Aconitase contains the iron-sulfur center Fe, S,.
An equilibrium mixture contains less than 10% citrate, but the isocitrate dehydrogenase reaction is exergonic, and draws
the aconitase reaction to the left.
The iron of the iron-sulfur center forms a complex with the substrate that involves two hydroxyl groups from citrate.
Aconitase is gtereospecific.
The reaction proceeds through the intermediate cis-aconitate.
Transcribed Image Text:Aconitase catalyzes the reversible isomerization of citrate to isocitrate. CH,CO0 CH,CO0 HO-C-co0 H- H-C-coo" HO-C-coo citrate isocitrate Determine which statements regarding aconitase are true. Aconitase contains the iron-sulfur center Fe, S,. An equilibrium mixture contains less than 10% citrate, but the isocitrate dehydrogenase reaction is exergonic, and draws the aconitase reaction to the left. The iron of the iron-sulfur center forms a complex with the substrate that involves two hydroxyl groups from citrate. Aconitase is gtereospecific. The reaction proceeds through the intermediate cis-aconitate.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
General Properties of d-Block Elements
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY