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Lipid storage droplets are the only human organelle known that is bound by phospholipid monolayer (see below). Why is there only a monolayer? PLIN proteins Phospholipid monolayer SSS Lipid droplet proteins Triglyceride SSSS Sterol Onal, G., Kutlu, O., Gozuacik, D., Emre, D. Lipid Droplets in Health and Disease. Lipids Health Dis 16, 128 (2017). https://doi.org/10.1186/s12944-017-0521-7 This is the ideal structure, since the hydrophobic tails would be able to interact with the hydrophobic lipids inside the droplet, while the hydrophilic head groups would be able to interact with the cytosol. The lipid droplets are still in the process of being synthesized; when mature they would have a lipid bilayer. The lipid droplets have evolved from bacterial endosymbionts, which only have monolayers. 0 A phospholipid bilayer would not work very well, since then the hydrophilic head groups on the inner leaflet would have to interact with the hydrophobic lipids on the inside of the lipid droplet.

Lipid storage droplets are the only human organelle known that is bound by phospholipid monolayer (see below). Why is there only a monolayer? PLIN proteins Phospholipid monolayer SSS Lipid droplet proteins Triglyceride SSSS Sterol Onal, G., Kutlu, O., Gozuacik, D., Emre, D. Lipid Droplets in Health and Disease. Lipids Health Dis 16, 128 (2017). https://doi.org/10.1186/s12944-017-0521-7 This is the ideal structure, since the hydrophobic tails would be able to interact with the hydrophobic lipids inside the droplet, while the hydrophilic head groups would be able to interact with the cytosol. The lipid droplets are still in the process of being synthesized; when mature they would have a lipid bilayer. The lipid droplets have evolved from bacterial endosymbionts, which only have monolayers. 0 A phospholipid bilayer would not work very well, since then the hydrophilic head groups on the inner leaflet would have to interact with the hydrophobic lipids on the inside of the lipid droplet.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Lipid storage droplets are the only human organelle known that is bound by phospholipid monolayer (see below). Why is there only a monolayer? PLIN proteins, Phospholipid monolayer SSS SSS Triglyceride Lipid droplet proteins E » Sterol ester Sterol Onal, G., Kutlu, O., Gozuacik, D., Emre, D. Lipid Droplets in Health and Disease. Lipids Health Dis 16, 128 (2017). https://doi.org/10.1186/s12944-017-0521-7 This is the ideal structure, since the hydrophobic tails would be able to interact with the hydrophobic lipids inside the droplet, while the hydrophilic head groups. would be able to interact with the cytosol. The lipid droplets are still in the process of being synthesized; when mature they would have a lipid bilayer. The lipid droplets have evolved from bacterial endosymbionts, which only have monolayers. A phospholipid bilayer would not work very well, since then the hydrophilic head groups on the inner leaflet would have to interact with the hydrophobic lipids on the inside of the lipid droplet.
Transcribed Image Text:Lipid storage droplets are the only human organelle known that is bound by phospholipid monolayer (see below). Why is there only a monolayer? PLIN proteins, Phospholipid monolayer SSS SSS Triglyceride Lipid droplet proteins E » Sterol ester Sterol Onal, G., Kutlu, O., Gozuacik, D., Emre, D. Lipid Droplets in Health and Disease. Lipids Health Dis 16, 128 (2017). https://doi.org/10.1186/s12944-017-0521-7 This is the ideal structure, since the hydrophobic tails would be able to interact with the hydrophobic lipids inside the droplet, while the hydrophilic head groups. would be able to interact with the cytosol. The lipid droplets are still in the process of being synthesized; when mature they would have a lipid bilayer. The lipid droplets have evolved from bacterial endosymbionts, which only have monolayers. A phospholipid bilayer would not work very well, since then the hydrophilic head groups on the inner leaflet would have to interact with the hydrophobic lipids on the inside of the lipid droplet.
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