Let's say that you are recording the membrane potential at the soma, as shown in the following

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Let's say that you are recording the membrane potential at the soma, as shown in the following
figure:
Neuron
Neuron 2
Neuron
Record .
An action potential in each of the presynaptic neurons at time t = 0 produces a postsynaptic
potential.
The shape of such potentials is described in the following graph:
-eani
67
Nen 2
Time (ms)
Assume that spatial and temporal summation hold, that the threshold for firing is 55mV, and that a
spike in a presynaptic neuron can be produced every 1ms.
1. It would take
consecutive spikes in neuron 1 (every 1ms, starting at t = 0) to
produce a spike in the postsynaptic neuron.
2. With spikes in neuron 2 at times t = 0, t = 2, and t = 4, a postsynaptic spike is produced around
ms.
3. Imagine that there is an additional presynaptic neuron, neuron 4, that produces an EPSP exactly
like that of neuron 1. Neurons 1, 3 and 4 fire an action potential at time t = 0. The membrane
potential at time t-2ms would be around
Membrane Potential (mv)
Transcribed Image Text:Let's say that you are recording the membrane potential at the soma, as shown in the following figure: Neuron Neuron 2 Neuron Record . An action potential in each of the presynaptic neurons at time t = 0 produces a postsynaptic potential. The shape of such potentials is described in the following graph: -eani 67 Nen 2 Time (ms) Assume that spatial and temporal summation hold, that the threshold for firing is 55mV, and that a spike in a presynaptic neuron can be produced every 1ms. 1. It would take consecutive spikes in neuron 1 (every 1ms, starting at t = 0) to produce a spike in the postsynaptic neuron. 2. With spikes in neuron 2 at times t = 0, t = 2, and t = 4, a postsynaptic spike is produced around ms. 3. Imagine that there is an additional presynaptic neuron, neuron 4, that produces an EPSP exactly like that of neuron 1. Neurons 1, 3 and 4 fire an action potential at time t = 0. The membrane potential at time t-2ms would be around Membrane Potential (mv)
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