Learning Target 12 Criteria for satisfactory score Reactants, reagents, or products of reactions must be valid chemical names or structures. Explanations must correctly explain the observation. Explanations must be logical. Tasks When compound 12.1 is treated with sodium methoxide, product A forms. When compound 12.2 is reacted under the same conditions, product B forms instead. 1. Define TsO¯ and explain it is a good leaving group for nucleophilic substitution and elimination reactions. 2. Predict the structures of compound A and B using conformational analysis of chair conformations and explain the divergent reactivity of the two isomeric tosylates. OTs OTs NaOH NaOH i-Pr. i-Pr,. A В heat heat 12.1 12.2 Figure 11: Elimination in cyclohexanes

Learning Target 12 Criteria for satisfactory score Reactants, reagents, or products of reactions must be valid chemical names or structures. Explanations must correctly explain the observation. Explanations must be logical. Tasks When compound 12.1 is treated with sodium methoxide, product A forms. When compound 12.2 is reacted under the same conditions, product B forms instead. 1. Define TsO¯ and explain it is a good leaving group for nucleophilic substitution and elimination reactions. 2. Predict the structures of compound A and B using conformational analysis of chair conformations and explain the divergent reactivity of the two isomeric tosylates. OTs OTs NaOH NaOH i-Pr. i-Pr,. A В heat heat 12.1 12.2 Figure 11: Elimination in cyclohexanes

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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